The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONIC‐BD)

• Published in: Bipolar disorders Vol. 21; no. 1; pp. 6 - 10
• Main Authors: Burdick, Katherine E., Millett, Caitlin E., Bonnín, Caterina del Mar, Bowie, Christopher R., Carvalho, Andre F., Eyler, Lisa T., Gallagher, Peter, Harvey, Philip D., Kessing, Lars V., Lafer, Beny, Langenecker, Scott A., Lewandowski, Kathryn E., López‐Jaramillo, Carlos, Marshall, David F., Martinez‐Aran, Anabel, McInnis, Melvin G., McIntyre, Roger S., Miskowiak, Kamilla W., Porter, Richard J., Purdon, Scot E., Ryan, Kelly A., Sumiyoshi, Tomiki, Torres, Ivan J., Van Rheenen, Tamsyn E., Vieta, Eduard, Woodward, Neil D., Yatham, Lakshmi N., Young, Allan H.
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.02.2019
• Subjects: Bipolar disorder
• ISSN: 1398-5647; 1399-5618
• DOI: 10.1111/bdi.12748

Bipolar Disorder (BD) is the 4 leading cause of disability worldwide among young people ages 10-24 years. Although the diagnosis is largely defined by the mood episodes associated with the illness, cognitive deficits are among the most persistent and disabling symptoms of illness and have a profound impact on clinical course and functional outcome. Specifically, trait-like impairment is common in the domains of attention, verbal learning, and executive function; these deficits contribute to functional disability and are targets for emerging treatments and preventions. Although considerable progress has been made over the past two decades, our understanding of the underlying causes of the cognitive deficits in BD remains surprisingly limited. As such, there are no approved treatments for this disabling symptom specific to BD. This article is protected by copyright. All rights reserved.