Synthesis, Characterization, and Properties Evaluation of Poly[(N-isopropylacrylamide)-co-ester]s

• Published in: Macromolecular chemistry and physics Vol. 208; no. 3; pp. 245 - 253
• Main Authors: Ren, Liqun, Agarwal, Seema
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 05.02.2007; WILEY‐VCH Verlag; Wiley
• Subjects: 1D and 2D NMR techniques; Applied sciences; Copolymerization; cyclic ketene acetals; degradable and water-soluble materials; Exact sciences and technology; free radical polymerization; N-isopropylacrylamide; NMR; Organic polymers; Physicochemistry of polymers; Preparation, kinetics, thermodynamics, mechanism and catalysts; Biological properties; copolymerization; Property composition relationship; Biodegradability; degradable and water-soluble materials; Solution copolymerization; Acrylamide derivative copolymer; 1D and 2D NMR techniques; Experimental study; Oxygen heterocycle; Reactivity ratio; Hydrolysis; Cloud point; Ester copolymer; NMR; free radical polymerization; Preparation; N-isopropylacrylamide; cyclic ketene acetals; Aqueous solution; Radical copolymerization; Ring opening copolymerization; Seven membered ring
• ISSN: 1022-1352; 1521-3935
• DOI: 10.1002/macp.200600484

Copolymerization behavior of cyclic ketene acetal like 5,6‐benzo‐2‐methylene‐1,3‐dioxepane (BMDO) with N‐isopropylacrylamide (NIPAAm) is studied by free radical polymerization. Structural characterization is done using 1D and 2D NMR techniques. Under optimized reaction conditions, quantitative ring‐opening of BMDO took place during the copolymerizations leading to the formation of poly(NIPAAm‐co‐ester)s. The reactivity ratios for the copolymerization of BMDO and NIPAAm were determined using Kelen–Tüdõs method and found to be rBMDO = 0.11 and rNIPAAm = 7.31. Copolymers with low mol‐% of BMDO were found to be soluble in water and also showed hydrolytic degradability. Different degradable copolymers could be generated with varied glass transition temperatures and lower critical solution temperatures (LCSTs).