Development of multi‐class computer‐aided diagnostic systems using the NICE/JNET classifications for colorectal lesions

• Published in: Journal of gastroenterology and hepatology Vol. 37; no. 1; pp. 104 - 110
• Main Authors: Okamoto, Yuki, Yoshida, Shigeto, Izakura, Seiji, Katayama, Daisuke, Michida, Ryuichi, Koide, Tetsushi, Tamaki, Toru, Kamigaichi, Yuki, Tamari, Hirosato, Shimohara, Yasutsugu, Nishimura, Tomoyuki, Inagaki, Katsuaki, Tanaka, Hidenori, Yamashita, Ken, Sumimoto, Kyoku, Oka, Shiro, Tanaka, Shinji
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.01.2022
• Subjects: Artificial Intelligence; Classification; Colonoscopes; colorectal; Colorectal Neoplasms - diagnostic imaging; computer‐aided diagnosis; Diagnosis; Diagnosis, Computer-Assisted; Endoscopy; Humans; Japan NBI Expert Team (JNET) classification; Lesions; narrow‐band imaging (NBI); NBI International Colorectal Endoscopic (NICE) classification; Sensitivity and Specificity; Statistical analysis; narrow-band imaging (NBI); Japan NBI Expert Team (JNET) classification; NBI International Colorectal Endoscopic (NICE) classification; computer-aided diagnosis; colorectal
• ISSN: 0815-9319; 1440-1746
• DOI: 10.1111/jgh.15682

Background and Aim Diagnostic support using artificial intelligence may contribute to the equalization of endoscopic diagnosis of colorectal lesions. We developed computer‐aided diagnosis (CADx) support system for diagnosing colorectal lesions using the NBI International Colorectal Endoscopic (NICE) classification and the Japan NBI Expert Team (JNET) classification. Methods Using Residual Network as the classifier and NBI images as training images, we developed a CADx based on the NICE classification (CADx‐N) and a CADx based on the JNET classification (CADx‐J). For validation, 480 non‐magnifying and magnifying NBI images were used for the CADx‐N and 320 magnifying NBI images were used for the CADx‐J. The diagnostic performance of the CADx‐N was evaluated using the magnification rate. Results The accuracy of the CADx‐N for Types 1, 2, and 3 was 97.5%, 91.2%, and 93.8%, respectively. The diagnostic performance for each magnification level was good (no statistically significant difference). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the CADx‐J were 100%, 96.3%, 82.8%, 100%, and 96.9% for Type 1; 80.3%, 93.7%, 94.1%, 79.2%, and 86.3% for Type 2A; 80.4%, 84.7%, 46.8%, 96.3%, and 84.1% for Type 2B; and 62.5%, 99.6%, 96.8%, 93.8%, and 94.1% for Type 3, respectively. Conclusions The multi‐class CADx systems had good diagnostic performance with both the NICE and JNET classifications and may aid in educating non‐expert endoscopists and assist in diagnosing colorectal lesions.