Diffusion- and perfusion-weighted MRI in therapeutic neurointerventional procedures

• Published in: Neuroradiology Vol. 43; no. 8; pp. 662 - 671
• Main Authors: CRONQVIST, M, RAMGREN, B, GEIJER, B, WIRESTAM, R, BRANDT, L, HOLTAS, S
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.08.2001
• Subjects: Adult; Aged; Biological and medical sciences; Brain - diagnostic imaging; Cerebral vascular malformation; Clinical Medicine; Diffusion; Female; Humans; Interventional neuroradiology; Intracranial Aneurysm - complications; Intracranial Aneurysm - diagnosis; Intracranial Arteriovenous Malformations - complications; Intracranial Arteriovenous Malformations - diagnosis; Keywords Diffusion-weighted imaging; Klinisk medicin; Magnetic Resonance Imaging - methods; Male; Medical and Health Sciences; Medical sciences; Medicin och hälsovetenskap; Neurology; Perfusion; Perfusion imaging; Prospective Studies; Radiography, Interventional; Radiologi och bildbehandling; Radiology, Nuclear Medicine and Medical Imaging; Vascular diseases and vascular malformations of the nervous system; Human; Intracranial; Nervous system diseases; Aneurysm; Instrumentation therapy; Cardiovascular disease; Operation; Congenital disease; Nuclear magnetic resonance imaging; Cerebral disorder; Vascular disease; Case study; Treatment; Perfusion; Central nervous system disease; Medical imagery; Embolization; Diagnosis; Diffusion; Cerebrovascular disease; Arteriovenous malformation
• ISSN: 0028-3940; 1432-1920; 1432-1920
• DOI: 10.1007/s002340100543

We describe three patients in whom we used MRI, including diffusion- and perfusion-weighted imaging (DWI, PWI) in conjunction with endovascular therapy. Two had intracranial aneurysms and one an arteriovenous malformation (AVM). The aneurysms were treated by coil embolisation or detachable balloons for proximal artery occlusion; the AVM was obliterated by intranidal glue injection. All patients had transient or permanent neurological deficits after treatment. The MRI techniques and interventional procedures are described and the DWI and PWI patterns found are correlated with the clinical features. We discuss how the information gained from MRI may increase our understanding of procedure-related complications and its potential impact on our therapeutic interventions, in order to prevent or limit the clinical consequences of such events.