Carcinoma of the liver

A study delineating epidemiologic factors in primary carcinoma of the liver was done utilizing the Atomic Bomb Casualty Commission autopsy series in Hiroshima and Nagasaki. The autopsy population includes persons exposed under various known conditions to the 1945 atomic bombs as well as unexposed in...

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Published inHuman pathology Vol. 2; no. 4; pp. 533 - 534
Main Author Jordan, Scott W.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.1971
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Abstract A study delineating epidemiologic factors in primary carcinoma of the liver was done utilizing the Atomic Bomb Casualty Commission autopsy series in Hiroshima and Nagasaki. The autopsy population includes persons exposed under various known conditions to the 1945 atomic bombs as well as unexposed individuals. No association between hepatoma and atomic bomb exposure was found, but interesting differences were delineated between the Nagasaki and Hiroshima populations. The prevalence rate of hepatic carcinoma was three times greater in Nagasaki than in Hiroshima, whereas the prevalence rate of cirrhosis of the liver was the same in both cities. The greater prevalence of primary carcinoma of the liver in Nagasaki was explained in part by the greater tendency of cirrhosis to be associated with hepatoma in that city.
AbstractList A study delineating epidemiologic factors in primary carcinoma of the liver was done utilizing the Atomic Bomb Casualty Commission autopsy series in Hiroshima and Nagasaki. The autopsy population includes persons exposed under various known conditions to the 1945 atomic bombs as well as unexposed individuals. No association between hepatoma and atomic bomb exposure was found, but interesting differences were delineated between the Nagasaki and Hiroshima populations. The prevalence rate of hepatic carcinoma was three times greater in Nagasaki than in Hiroshima, whereas the prevalence rate of cirrhosis of the liver was the same in both cities. The greater prevalence of primary carcinoma of the liver in Nagasaki was explained in part by the greater tendency of cirrhosis to be associated with hepatoma in that city.
Author Jordan, Scott W.
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Cites_doi 10.1002/1097-0142(1967)20:5<627::AID-CNCR2820200509>3.0.CO;2-4
10.1002/1097-0142(196406)17:6<757::AID-CNCR2820170611>3.0.CO;2-9
10.1002/1097-0142(197007)26:1<69::AID-CNCR2820260108>3.0.CO;2-0
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References Mori (bib4) 1967; 20
Schreiber, Kato, Robertson (bib1) 1970; 26
Patton, Horn (bib5) 1964; 17
Gall (bib2) 1960; 36
Kato, H., Yano, K., and Johnson, K. G.: Study of cardiovascular disease in Hiroshima and Nagasaki mortality. Atomic Bomb Casualty Commission Research Protocol 109–165
Patton (10.1016/S0046-8177(71)80060-6_bib5) 1964; 17
Gall (10.1016/S0046-8177(71)80060-6_bib2) 1960; 36
10.1016/S0046-8177(71)80060-6_bib3
Mori (10.1016/S0046-8177(71)80060-6_bib4) 1967; 20
Schreiber (10.1016/S0046-8177(71)80060-6_bib1) 1970; 26
References_xml – volume: 20
  start-page: 627
  year: 1967
  end-page: 631
  ident: bib4
  article-title: Cirrhosis and primary cancer of the liver Comparative study in Tokyo and Cincinnati
  publication-title: Cancer
  contributor:
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– volume: 26
  start-page: 69
  year: 1970
  ident: bib1
  article-title: Primary carcinoma of the lvier in Hiroshima and Nagasaki, Japan
  publication-title: Cancer
  contributor:
    fullname: Robertson
– volume: 17
  start-page: 757
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  end-page: 768
  ident: bib5
  article-title: Primary liver carcinoma. Autopsy study of 60 cases
  publication-title: Cancer
  contributor:
    fullname: Horn
– volume: 36
  start-page: 241
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  ident: bib2
  article-title: Posthepatic, postnecrotic and nutritional cirrhosis. A pathologic analysis
  publication-title: Am. J. Path.
  contributor:
    fullname: Gall
– volume: 20
  start-page: 627
  year: 1967
  ident: 10.1016/S0046-8177(71)80060-6_bib4
  article-title: Cirrhosis and primary cancer of the liver Comparative study in Tokyo and Cincinnati
  publication-title: Cancer
  doi: 10.1002/1097-0142(1967)20:5<627::AID-CNCR2820200509>3.0.CO;2-4
  contributor:
    fullname: Mori
– volume: 36
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  year: 1960
  ident: 10.1016/S0046-8177(71)80060-6_bib2
  article-title: Posthepatic, postnecrotic and nutritional cirrhosis. A pathologic analysis
  publication-title: Am. J. Path.
  contributor:
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– volume: 17
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  year: 1964
  ident: 10.1016/S0046-8177(71)80060-6_bib5
  article-title: Primary liver carcinoma. Autopsy study of 60 cases
  publication-title: Cancer
  doi: 10.1002/1097-0142(196406)17:6<757::AID-CNCR2820170611>3.0.CO;2-9
  contributor:
    fullname: Patton
– volume: 26
  start-page: 69
  year: 1970
  ident: 10.1016/S0046-8177(71)80060-6_bib1
  article-title: Primary carcinoma of the lvier in Hiroshima and Nagasaki, Japan
  publication-title: Cancer
  doi: 10.1002/1097-0142(197007)26:1<69::AID-CNCR2820260108>3.0.CO;2-0
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SubjectTerms Adenoma, Bile Duct - epidemiology
Adenoma, Bile Duct - etiology
Aged
Carcinoma, Hepatocellular - epidemiology
Carcinoma, Hepatocellular - etiology
Female
Humans
Japan
Liver Cirrhosis - epidemiology
Liver Neoplasms - epidemiology
Liver Neoplasms - etiology
Male
Middle Aged
Neoplasms, Radiation-Induced - epidemiology
Nuclear Warfare
Title Carcinoma of the liver
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https://www.ncbi.nlm.nih.gov/pubmed/4329514
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