Carcinoma of the liver

A study delineating epidemiologic factors in primary carcinoma of the liver was done utilizing the Atomic Bomb Casualty Commission autopsy series in Hiroshima and Nagasaki. The autopsy population includes persons exposed under various known conditions to the 1945 atomic bombs as well as unexposed in...

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Bibliographic Details
Published inHuman pathology Vol. 2; no. 4; pp. 533 - 534
Main Author Jordan, Scott W.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.1971
Subjects
Adenoma, Bile Duct - epidemiology
Adenoma, Bile Duct - etiology
Aged
Carcinoma, Hepatocellular - epidemiology
Carcinoma, Hepatocellular - etiology
Female
Humans
Japan
Liver Cirrhosis - epidemiology
Liver Neoplasms - epidemiology
Liver Neoplasms - etiology
Male
Middle Aged
Neoplasms, Radiation-Induced - epidemiology
Nuclear Warfare
Japan
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Summary:A study delineating epidemiologic factors in primary carcinoma of the liver was done utilizing the Atomic Bomb Casualty Commission autopsy series in Hiroshima and Nagasaki. The autopsy population includes persons exposed under various known conditions to the 1945 atomic bombs as well as unexposed individuals. No association between hepatoma and atomic bomb exposure was found, but interesting differences were delineated between the Nagasaki and Hiroshima populations. The prevalence rate of hepatic carcinoma was three times greater in Nagasaki than in Hiroshima, whereas the prevalence rate of cirrhosis of the liver was the same in both cities. The greater prevalence of primary carcinoma of the liver in Nagasaki was explained in part by the greater tendency of cirrhosis to be associated with hepatoma in that city.
ISSN:0046-8177
1532-8392
DOI:10.1016/S0046-8177(71)80060-6