Marked Left Ventricular Hypertrophy in Children on Tacrolimus (FK506) After Orthotopic Liver Transplantation

Although the cardiac effects of tacrolimus (FK506) have not been well documented, clinical cases of children on FK506 who developed hypertrophic obstructive cardiomyopathy have been reported. We report 2 cases of marked concentric hypertrophy of the left ventricular myocardium found at autospy in ch...

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Bibliographic Details
Published inThe American journal of cardiology Vol. 81; no. 10; pp. 1277 - 1280
Main Authors Chang, Ruey-Kang R., Alzona, Maria, Alejos, Juan, Jue, Kenneth, McDiarmid, Suzanne V.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 15.05.1998
Elsevier Limited
Subjects
Cardiovascular disease
Child
Children & youth
Female
Heart
Humans
Hypertrophy, Left Ventricular - chemically induced
Hypertrophy, Left Ventricular - pathology
Immunosuppressive Agents - adverse effects
Infant, Newborn
Liver
Liver Transplantation
Male
Medical research
Tacrolimus - adverse effects
Transplants & implants
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Summary:Although the cardiac effects of tacrolimus (FK506) have not been well documented, clinical cases of children on FK506 who developed hypertrophic obstructive cardiomyopathy have been reported. We report 2 cases of marked concentric hypertrophy of the left ventricular myocardium found at autospy in children on FK506.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(98)00126-X