The development of a latex agglutination inhibition assay for the determination of foetal calf serum in viral vaccines

• Published in: Biologicals Vol. 18; no. 1; pp. 45 - 48
• Main Authors: Sladoljev, S., Treščec, Andja, Cvetković, Maja, Beck, M., Juzbašić, Mirjam
• Format: Journal Article
• Language: English
• Published: Kent Elsevier Ltd 1990; Elsevier Science
• Subjects: Animals; Biological and medical sciences; Blood; Cattle; Drug Contamination - prevention & control; Fundamental and applied biological sciences. Psychology; Horses; Humans; Latex Fixation Tests - methods; Microbiology; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Species Specificity; Techniques used in virology; Viral Vaccines - analysis; Virology; Performance evaluation; Bovine; Biosynthesis; Vaccine; Virus; Vertebrata; Specificity; Mammalia; Fetus; Serum; Artiodactyla; Detection; Ungulata

A simple but specific, sensitive and reproducible latex agglutination inhibition assay for the determination of foetal calf sera in viral vaccines has been developed and standardized. The detection limit was at nanogram level. The assay procedure requires two pipetting steps, a short centrifugation...