The imaging features of gastrointestinal stromal tumours

Gastrointestinal stromal tumours (GISTs) are a rare group of mesenchymal neoplasms that occur predominantly in the gastrointestinal tract. Previously GISTs were classified as smooth muscle tumours referred to as leiomyomas, leiomyosacromas or leiomyoblastomas. However, with the advent of immunohisto...

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Published inEuropean journal of radiology Vol. 60; no. 3; pp. 431 - 438
Main Authors O'Sullivan, P.J., Harris, A.C., Ho, S.G., Munk, P.L.
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.12.2006
Elsevier Science
Subjects
Biological and medical sciences
Contrast Media
Diagnostic Imaging
Gastroenterology. Liver. Pancreas. Abdomen
Gastrointestinal Stromal Tumors - diagnosis
Gastrointestinal Stromal Tumors - pathology
Gastrointestinal Stromal Tumors - therapy
Gastrointestinal tract
Humans
Medical sciences
Oncology
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
Tumour
Oncology
Gastrointestinal tract
Tumour
Digestive diseases
Gastrointestinal
Gastrointestinal stromal tumor
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Summary:Gastrointestinal stromal tumours (GISTs) are a rare group of mesenchymal neoplasms that occur predominantly in the gastrointestinal tract. Previously GISTs were classified as smooth muscle tumours referred to as leiomyomas, leiomyosacromas or leiomyoblastomas. However, with the advent of immunohistochemistry, GISTs are now defined by the identification of cKit positivity. This is now used to select patients with metastatic disease who may respond to chemotherapeutic agents such as the tyrosine kinase inhibitor, STI-571. In this pictorial essay we have attemped to describe the range of imaging findings of GISTs that can suggest a pre-biopsy diagnosis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2006.06.017