A New Trinor-guaiane Sesquiterpene from an Indonesian Soft Coral Anthelia sp

A new trinor-guaiane sesquiterpene has been isolated from an Indonesian soft coral Anthelia sp. The planar structure, possessing an octahydroazulene skeleton, and relative stereochemistry were established by analyzing 1D and 2D NMR data, including NOE experiments. Its absolute stereochemistry was el...

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Bibliographic Details
Published inNatural product communications Vol. 10; no. 11; pp. 1907 - 1910
Main Authors Hanif, Novriyandi, Murni, Anggia, Yamauchi, Marie, Higashi, Masahiro, Tanaka, Junichi
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.11.2015
Subjects
Animals
Anthozoa - chemistry
Magnetic Resonance Spectroscopy
Molecular Structure
Sesquiterpenes, Guaiane - chemistry
Sesquiterpenes, Guaiane - isolation & purification
Sesquiterpene
Cytotoxicity
Soft coral
Trinor-guaiane
Anthelia sp
Indonesia
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Summary:A new trinor-guaiane sesquiterpene has been isolated from an Indonesian soft coral Anthelia sp. The planar structure, possessing an octahydroazulene skeleton, and relative stereochemistry were established by analyzing 1D and 2D NMR data, including NOE experiments. Its absolute stereochemistry was elucidated to be 1S, 4S, 7R, and 10R by comparing observed and calculated optical rotation values. The new compound showed weak cytotoxicity against NBT-T2 cells.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1501001124