Positive outcomes with neoadjuvant chemotherapy in the management of colovesical fistula in cancer: a case report and literature review

Colovesical fistula (CVF) is usually developed from colonic diverticulitis, followed by tumor. Traditional surgery is usually completed in one or more stages. For complex cancerous CVF, radical resection is more difficult. We report a 62-year-old male patient diagnosed with sigmoid colon cancer comb...

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Published inFrontiers in pharmacology Vol. 14; p. 1284316
Main Authors Tang, Song, Li, Xinjun, Guo, Donghua, Zhuo, Fan
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 15.01.2024
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Summary:Colovesical fistula (CVF) is usually developed from colonic diverticulitis, followed by tumor. Traditional surgery is usually completed in one or more stages. For complex cancerous CVF, radical resection is more difficult. We report a 62-year-old male patient diagnosed with sigmoid colon cancer combined with sigmoid vesical fistula. In the course of treatment, in addition to conventional surgery, neoadjuvant chemotherapy (NAC) was innovatively used. The sigmoid tumor and fistula were significantly shrunken. Radical surgery achieved negative margins.
Bibliography:Edited by: Sheema Khan, The University of Texas Rio Grande Valley, United States
Bahareh Hajikhani, Shahid Beheshti University of Medical Sciences, Iran
Reviewed by: Rajesh Nachiappa Ganesh, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), India
Hessam Yousefian, Iran Medical Council, Iran
Sudhir Kumar, Medical College of Wisconsin, United States
ISSN:1663-9812
1663-9812
DOI:10.3389/fphar.2023.1284316