Special characteristics and potential for dynamic function studies with PET

The possibility of utilizing the PET approach to the investigation of dynamic physiologic processes has not been limited so far by radiation exposure to the patient but rather considerations by the technical limitations of PET imaging devices. In the past few years, several PET designs have been opt...

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Bibliographic Details
Published inSeminars in nuclear medicine Vol. 11; no. 1; pp. 13 - 23
Main Author Ter-Pogossian, Michel M.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 1981
Subjects
Humans
Mathematics
Physiology - methods
Radiation Injuries - prevention & control
Tomography, Emission-Computed - instrumentation
Tomography, Emission-Computed - trends
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Summary:The possibility of utilizing the PET approach to the investigation of dynamic physiologic processes has not been limited so far by radiation exposure to the patient but rather considerations by the technical limitations of PET imaging devices. In the past few years, several PET designs have been optimized specifically for fast dynamic studies. The most recent of these designs incorporates cesium fluoride detectors to achieve high counting rate capabilities. At this time, the value of fast dynamic studies with PET can be only theorized but expectations for this modality rest on solid physiologic hypotheses. The incorporation of time-of-flight information into the PET reconstruction process promises to further enhance the capabilities of fast PET devices by the improvement of temporal resolution through signalto-noise ratio increase. PET devices incorporating time-of-flight information are beyond the drawing board stage and are now under construction.
ISSN:0001-2998
1558-4623
DOI:10.1016/S0001-2998(81)80049-9