Incidence and profile of benign epithelial tumors of salivary glands from a single center in Northeast of Brazil

• Published in: Medicina oral, patología oral y cirugía bucal Vol. 26; no. 1; pp. e108 - e113
• Main Authors: Santana, B-W, Silva, L-P, Serpa, M-S, Borges, M-D, Moura, S-R, Silveira, M-M, Sobral, A-P
• Format: Journal Article
• Language: English
• Published: Spain Medicina Oral S.L 01.01.2021
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Brazil - epidemiology; Child; Dentistry; Female; Humans; Incidence; Middle Aged; Neoplasms, Glandular and Epithelial; Retrospective Studies; Salivary Gland Neoplasms - epidemiology; Salivary Glands; Young Adult; Brazil
• ISSN: 1698-6946; 1698-4447; 1698-6946
• DOI: 10.4317/medoral.24056

Benign tumors of the salivary glands are a group of lesions with varied histopathological and clinical spectrum. The aim was to determine the incidence and clinicopathological characteristics of benign salivary gland neoplasms diagnosed between 2007 and 2016 in a single center located in northeastern Brazil. Records regarding sex, age, anatomical location, histopathological subtype and treatment were retrieved, and data were analyzed using the Stata/IC software (version 12.0). There were above 7,100 cases of neoplasms in the head and neck region, of which 403 corresponded to salivary gland neoplasms. Of these, 238 (59%) were benign, being pleomorphic adenoma (PA) the most frequent neoplasm (n=178; 74.8%), followed by Warthin's tumor (WT) (n=23; 9.7%). Overall, most cases occurred in females (n=136; 57.1%) and age ranged from 11 to 83 years. The parotid gland (n=188; 79%) was the most common anatomical site, and all patients were treated by surgical excision. Of the cases diagnosed as PA, malignant transformation to carcinoma ex-pleomorphic adenoma (CAEXPA) occurred in 7 (3.9%) cases. The present study confirmed the clinical and demographic profile of benign salivary gland neoplasms, which contributes to the continuous knowledge of current data about these lesions.