PCP prophylaxis in paediatric HIV infection: time for a change?

Development and widespread implementation of guidelines for the prevention of Pneumocystis carinii pneumonia (PCP) have not eliminated the disease. To treat PCP, pediatricians would need to decide when to discontinue prophylaxis in HIV-infected infants since continuous prophylaxis may prevent Pneumo...

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Bibliographic Details
Published inThe Lancet (British edition) Vol. 344; no. 8914; pp. 5 - 6
Main Authors Kovacs, JosephA, Kovacs, AndreaA.S.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 02.07.1994
Elsevier Limited
Subjects
AIDS-Related Opportunistic Infections - immunology
AIDS-Related Opportunistic Infections - prevention & control
AIDS/HIV
CD4-Positive T-Lymphocytes
Child
Health care
HIV
HIV Infections - diagnosis
Human immunodeficiency virus
Humans
Infant
Leukocyte Count
Pediatrics
Pneumonia
Pneumonia, Pneumocystis - immunology
Pneumonia, Pneumocystis - prevention & control
Prophylaxis
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Summary:Development and widespread implementation of guidelines for the prevention of Pneumocystis carinii pneumonia (PCP) have not eliminated the disease. To treat PCP, pediatricians would need to decide when to discontinue prophylaxis in HIV-infected infants since continuous prophylaxis may prevent Pneumocystis carinii infection and change the natural history of PCP.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(94)91042-1