The Effect of Chorionic Villus Sampling on Fetal Heart Rate

• Published in: Fetal diagnosis and therapy Vol. 20; no. 2; pp. 116 - 120
• Main Authors: Akhlaghpoor, Shahram, Hosseinipoor, Taraneh
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.03.2005; S. Karger AG
• Subjects: beta-Thalassemia - diagnosis; Biological and medical sciences; Birth control; Chorionic Villi Sampling - adverse effects; Female; Gestational Age; Gynecology. Andrology. Obstetrics; Heart Rate, Fetal; Hormonal contraception; Humans; Medical sciences; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Fetal heart rate; Prenatal diagnosis; Chorionic villus sampling; Pregnancy; Prenatal; Heart rate; Prenatal Diagnosis; Samplings; Fetus; Chorionic villus sampling Fetal heart rate; Chorionic villi
• ISSN: 1015-3837; 1421-9964
• DOI: 10.1159/000082434

Objective: Fetal heart rate (FHR) variation during chorionic villus sampling (CVS) is a controversial topic. Limited studies have been published on this subject. Our study intended to evaluate the effects of CVS on the FHR. Method: One hundred and sixty-five patients undergoing first-trimester elective CVS for prenatal diagnosis of β-thalassemia were entered into a prospective study. M-mode FHR was obtained before and immediately after CVS in the patients. Potentially confounding variables also recorded included: gestational age, number of needle passes and placental location. Results: FHR values before and after CVS were compared using the paired t test and showed no statistically significant differences by 95% confidence. No differences were found in data analyzing gestational age, number of needle passes or placental location. Conclusion: We were unable to detect any significant change in FHR after performing CVS. It seems that FHR is generally not altered by CVS.