Essential Oil Composition of Bupleurum praealtum and Bupleurum affine : New Natural Constituents

• Published in: Plants (Basel) Vol. 13; no. 15; p. 2076
• Main Authors: Nešić, Milica D, Nešić, Milan S, Dimitrijević, Milan Ž, Radulović, Niko S
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.08.2024
• Subjects: Acetic acid; Acids; Bupleurum; Chemical composition; Constituents; Ecological adaptation; Essential oils; Esters; Flowers & plants; Herbal medicine; Hydrocarbons; Instrument industry; isomeric praealtaesters; NMR; Nuclear magnetic resonance; Oils & fats; perillyl esters; Pharmaceuticals; Phytochemicals; plant volatiles; Simulation; spectral simulation; Serbia; United States; China; Bupleurum; NMR; isomeric praealtaesters; 4-alkyl acetate; plant volatiles; spectral simulation; perillyl esters
• ISSN: 2223-7747; 2223-7747
• DOI: 10.3390/plants13152076

This study explores the chemical composition of essential oils from two Serbian species (Apiaceae), L. and L., traditionally recognized in Chinese medicine for their therapeutic potential but less studied for their essential oils. Through GC-MS analysis, we identified 230 constituents, revealing distinct profiles between the species. Perillyl 2-methylbutanoate was identified in oil for the first time, confirmed using synthetic approaches and characterized by advanced spectroscopic techniques, including two-dimensional NMR and spin-simulation of H NMR spectra. Additionally, new natural compounds, including tentatively identified 4-decyl acetate and 4-undecyl acetate, were discovered. The study also reports five stereoisomeric esters of tetradeca-5,7,9,11-tetraen-1-ol. These findings significantly contribute to the understanding of the phytochemical diversity within the genus and underscore potential differences in ecological adaptations or biosynthetic pathways among species.