Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association : Report of a Case

The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems,...

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Published inCase reports in hematology Vol. 2012; no. 2012; pp. 1 - 4
Main Authors Regragui, S., Amelal, S., Astati, S., Zine, M., Alami Drideb, N., al-Bouzidi, A., Messaoudi, N., Benkirane, M., Doghmi, K., Mikdame, M.
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Puplishing Corporation 01.01.2012
Hindawi Publishing Corporation
Hindawi Limited
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Summary:The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems, organ transplants, and cancer. Other forms are secondary to drugs including antimitotics. We report the case of a patient followed for acute myelogenous leukemia. She received induction chemotherapy combining daunorubicin and cytarabine, complicated by thrombotic thrombocytopenic purpura.
Bibliography:Academic Editors: S. Aref and Y. Matsukawa
ISSN:2090-6560
2090-6579
DOI:10.1155/2012/806476