Crystallization and Preliminary X-Ray Study of Agkistrodon halys blomhoffii Phospholipase A2 Complexed with a Specific Inhibitor

• Published in: Journal of biochemistry (Tokyo) Vol. 113; no. 4; pp. 411 - 412
• Main Authors: Tomoo, Koji, Fujiii, Shinobu, Ishida, Toshimasa, Inoue, Masaloshi, Ikeda, Kiyoshi, Samejima, Yuji, Iwama, Seiji, Katsumura, Shigeo
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.04.1993
• Subjects: Animals; Crotalid Venoms - enzymology; Crystallization; Phospholipases A - antagonists & inhibitors; Phospholipases A - chemistry; Phospholipases A2; X-Rays

Phospholipase A2 from the venom of Agkistrodon halys blomhoffii has been crystallized as a complex with a specific inhibitor, (iS)-2-dodecanoyl-amino-3-hexanol-l-phosphoglycol. The complex crystals belong to the hexagonal space group, P6i22 (or P6622), with cell dimensions of a= 6 = 61.13 A, and c =...