Lipofibromatosis presenting as a pediatric neck mass

• Published in: International journal of pediatric otorhinolaryngology Vol. 68; no. 12; pp. 1545 - 1549
• Main Authors: Herrmann, B.W., Dehner, L.P., Forsen, J.W.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.12.2004
• Subjects: Child; Diagnosis, Differential; Female; Fibroma - pathology; Fibroma - surgery; Head and Neck Neoplasms - pathology; Humans; Lipofibromatosis; Lipoma - pathology; Lipoma - surgery; Magnetic Resonance Imaging; Neck mass; Pediatric; Prognosis; Tomography, X-Ray Computed; Treatment Outcome; Neck mass; Lipofibromatosis; Pediatric
• ISSN: 0165-5876; 1872-8464
• DOI: 10.1016/j.ijporl.2004.07.004

Lipofibromatosis is a recently described, benign neoplasm that presents in the pediatric population [J.F. Fetsch, M. Miettinen, W.B. Laskin, M. Michal, F.M. Enzinger, A clinicopathologic study of 45 pediatric soft tissue tumors with an admixture of adipose tissue and fibroblastic elements, and a proposal for classification as lipofibromatosis, Am. J. Surg. Pathol. 24 (2000) 1491–1500]. It is a rare soft tissue tumor histologically distinct from other fibromatoses such as juvenile fibromatosis, fibrous hamartoma of infancy, calcifying aponeurotic fibroma, and lipoblastoma. Distinguishing histopathologic features of lipofibromatosis include abundant and disorganized adipose lobules traversed by bundles of spindled fibroblast-like cells. It most commonly presents in the extremities. We present a case involving a young girl, which we believe represents the first report of lipofibromatosis involving the neck.