Comorbid personality disorder predicts suicide after major depression: a 10-year follow-up
To identify psychopathological predictors for suicide in a population of major depressed Diagnostic Statistical Manual-III (DSM-III) in-patients. A total of 210 previous participants in multicentre antidepressant drug trials, carried out in a randomized double-blind design, were followed prospective...
Saved in:
Published in | Acta psychiatrica Scandinavica Vol. 107; no. 6; pp. 436 - 440 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Blackwell
01.06.2003
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | To identify psychopathological predictors for suicide in a population of major depressed Diagnostic Statistical Manual-III (DSM-III) in-patients.
A total of 210 previous participants in multicentre antidepressant drug trials, carried out in a randomized double-blind design, were followed prospectively through a maximum of 10 years. Patients with a drug or alcohol abuse were excluded. The association between suicide and the pretreatment psychopathological profile was analysed using survival statistics.
The suicide rate for non-melancholic depressed patients was significantly higher than for melancholic depressed patients. Comorbid personality disorder was independently associated with an increased suicide rate [relative hazard 3.41(CI: 1.15-10.10)].
The study indicates that the non-melancholic aspect of depression, and especially comorbid personality disorder, is associated with an increased suicidal vulnerability. |
---|---|
Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-News-3 content type line 23 |
ISSN: | 0001-690X 1600-0447 |
DOI: | 10.1034/j.1600-0447.2003.02048.x |