Tubulolobular carcinoma of the breast: Clinical, mammographic and sonographic findings
To determine and quantitate radiologic characteristics of tubulolobular carcinoma of the breast and to report clinical and pathologic findings. A retrospective review of records of 2872 women who received a diagnosis of breast carcinoma between January 1988 and January 2006 revealed 26 histopatholog...
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Published in | European journal of radiology Vol. 60; no. 3; pp. 418 - 424 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Shannon
Elsevier Ireland Ltd
01.12.2006
Elsevier Science |
Subjects | |
Online Access | Get full text |
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Summary: | To determine and quantitate radiologic characteristics of tubulolobular carcinoma of the breast and to report clinical and pathologic findings.
A retrospective review of records of 2872 women who received a diagnosis of breast carcinoma between January 1988 and January 2006 revealed 26 histopathologically proven tubulolobular carcinoma of the breast. Analysis included history; findings at physical examination, mammography, and sonography (US) at the time of diagnosis and in postoperative follow-up, and histopathological results.
At physical examination, palpable mass was present in 85% (
n
=
22) of the patients. The mammographic findings were mass in 17 (65%), asymmetric focal density in 2 (8%), architectural distortion in 2 (8%) and negative mammograms in 5 (19%) of the 26 patients. US depicted 25 masses in 24 patients, all of which were hypoechoic, with spiculated (
n
=
13) or microlobulated (
n
=
12) margins. The cancer was clinically occult in 12% (
n
=
3), mammographically occult in 19% (
n
=
5), and radiologically occult in 4% (
n
=
1) of the patients. Histologically, the mean size of the tumor was 1.7
cm and 18 (69%) patients were node negative.
Tubulolobular carcinoma of the breast usually manifests clinically as a firm, immobile mass and mammographically as a spiculated or ill-defined, irregular, isodense mass without microcalcifications. Common findings on sonography include a homogeneously hypoechoic, spiculated or microlobulated mass with posterior acoustic shadowing or normal acoustic transmission. Tubulolobular carcinoma should be included in the differential diagnosis for breast masses with these imaging features. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0720-048X 1872-7727 |
DOI: | 10.1016/j.ejrad.2006.06.011 |