Osteopontin and osteoprotegerin in atherosclerotic plaque - are they significant markers of plaque vulnerability?

• Published in: Romanian journal of morphology and embryology Vol. 61; no. 3; pp. 793 - 801
• Main Authors: Strobescu-Ciobanu, Cristina, Giuşcă, Simona Eliza, Căruntu, Irina Draga, Amălinei, Cornelia, Rusu, Andreea, Cojocaru, Elena, Popa, Radu Florin, Lupaşcu, Cristian Dumitru
• Format: Journal Article
• Language: English
• Published: Romania Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 01.01.2020
• Subjects: Biomarkers; Female; Humans; Male; Original Paper; Osteopontin; Osteoprotegerin; Plaque, Atherosclerotic; Vascular Calcification

Atherosclerosis (ATS) is still considered as a major, global health problem. For a deeper understanding of its pathogenesis, in the last years the research was translated from tissue visible events to molecular mechanisms. Osteopontin (OPN) and osteoprotegerin (OPG) are two molecules that have been...