Spinal cord stimulation in patients suffering from chronic pain after surgery for spinal intradural tumors: A case report and literature summary

• Published in: Pain practice Vol. 22; no. 8; pp. 746 - 752
• Main Authors: Noordhof, Robin K., Vinke, Saman, Kurt, Erkan
• Format: Journal Article
• Language: English
• Published: United States John Wiley and Sons Inc 01.11.2022
• Subjects: Case Report; chronic pain; Chronic Pain - complications; Chronic Pain - therapy; Female; Humans; Meningeal Neoplasms - complications; Meningioma - complications; Meningioma - surgery; Middle Aged; Neuralgia - etiology; Neuralgia - therapy; Quality of Life; Spinal Cord; Spinal Cord Injuries - complications; spinal cord injury; spinal cord stimulation; Spinal Cord Stimulation - adverse effects; spinal intradural tumor; Spinal Neoplasms - complications; Treatment Outcome; spinal cord injury; spinal intradural tumor; chronic pain; spinal cord stimulation
• ISSN: 1530-7085; 1533-2500
• DOI: 10.1111/papr.13156

Background The prevalence of pain after treatment of a spinal intradural tumor is remarkably high, approximately up to 40% of the patients suffer from central neuropathic pain. Publications on spinal cord stimulation (SCS) and its effect on pain caused by intradural spinal tumors are rare. We discuss the case of a patient suffering from chronic pain after removal of a Th7 level meningioma who was successfully treated with SCS and give an overview of the literature. Methods MEDLINE database was searched for neuropathic pain and intradural tumors. Results The initial search identified 35 articles, including hand‐searched manuscripts. Six articles were included for analysis. Case Report A 57‐year‐old female suffers from neuropathic pain in both legs after surgical removal of a Th7 level intradural meningioma. Postoperative magnetic resonance imaging shows no gross abnormalities, although she developed chronic pain in both legs. Pain in combination with side effects of analgesic intake are too disabling to have decent quality of life. A successful implantation of SCS is achieved at Th5 level as a treatment for the central neuropathic pain, and, at 36 months follow‐up, there is significant pain relief and almost complete discontinuation of analgesics. Discussion Central pain from spinal intradural tumors may have a different mechanism of origin than pain seen after an acute spinal cord injury (SCI). However, the basic principles of neuromodulation are the same in both etiologies, as for successful stimulation intact pathways in the spinal cord are necessary. The efficacy of SCS as treatment in intradural spinal tumors is rarely described as only a handful of case reports are published. Interestingly, the case reports show that stimulation both above and below the lesion can be effective. In patients with incomplete SCI or intradural tumor resection stimulation below the lesion could be considered and tried in a trial setting before definitive implantation.