Systematic review and health risk assessment of arsenic and lead in the fished shrimps from the Persian gulf

• Published in: Food and chemical toxicology Vol. 113; pp. 278 - 286
• Main Authors: Fakhri, Yadolah, Mohseni-Bandpei, Anoushiravan, Oliveri Conti, Gea, Ferrante, Margherita, Cristaldi, Antonio, Jeihooni, Ali Khani, Karimi Dehkordi, Maryam, Alinejad, Abdolazim, Rasoulzadeh, Hassan, Mohseni, Seyed Mohsen, Sarkhosh, Maryam, Keramati, Hassan, Moradi, Bigard, Amanidaz, Nazak, Baninameh, Zahra
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2018
• Subjects: Adolescent; Adult; Animals; arsenic; Arsenic - analysis; bioaccumulation; Bioconcentration; Carcinogenic risk; Carcinogens - analysis; Crustacea - chemistry; Crustacea - classification; Female; Fenneropenaeus indicus; fish; Food safety; guidelines; health effects assessments; heavy metals; human health; Humans; Indian Ocean - epidemiology; ingestion; Iran; lead; Lead - analysis; Litopenaeus vannamei; Male; meta-analysis; Metapenaeus; Middle Aged; mouth neoplasms; Mouth Neoplasms - chemically induced; Mouth Neoplasms - epidemiology; muscles; Muscles - chemistry; Panulirus homarus; Penaeus semisulcatus; Persian Gulf; Population Health; risk; Risk Assessment; Seafood - analysis; seafoods; shrimp; Shrimps; Species Specificity; systematic review; toxicology; World Health Organization; Young Adult; Iran; Persian Gulf; Shrimps; Pb; As; Carcinogenic risk; Risk assessment; Food safety; Bioconcentration
• ISSN: 0278-6915; 1873-6351; 1873-6351
• DOI: 10.1016/j.fct.2018.01.046

The ingestion of heavy metals through contaminated seafood can causes significant outcomes on human health. In recent years, consume fishes and shrimps has increased in Iran, and several study about heavy metals content in fishes and shrimps from Persian Gulf were carried out to check their food safety. The aims of these systematic reviews and meta-analysis was to summarize the evidence on the relation of the intakes of Arsenic (As) and lead (Pb) levels, based on the origin and sub-groups of shrimp species consumed, Hence that we can estimate the risk of oral cancer induced by Pb in these groups of shrimp from the persian gulf. We carried out a search of all suitable studies published between 1995 and 2017 in Scopus, Science Direct, PubMed and Web of Science databases. Since the heterogeneity among studied was significant, we used the random effect model (REM) to perform meta-analysis of data. Data were obtained from 9 articles (14 studies), with 511 samples, and it was reported that pooled levels of As and Pb in the muscle shrimps were 1.37 (95% CI: 0.66–2.08 mg/kg d.w.) and 0.58 (95% CI: 0.33–0.82 mg/kg d.w.), respectively. This pooled levels in muscle shrimps were higher than safe dose reported on Food and Agriculture Organization/World Health Organization guidelines (FAO/WHO). The rank order of shrimps species based on As was Panulirus homarus > Penaeus semisulcatus and for the Pb levels was Litopenaeus vannamei > Panulirus homarus > Fenneropenaeus indicus > Metapenaeus affinis. The lowest and highest risk levels of oral cancer, divided by consumers age groups, were respectively 45–54 (6.94E-04) and 15–24 (8.42E-04) for the Pb, Incremental Lifetime Cancer Risk (ILCR) of Pb and As was higher than 10-4 respectively. [Display omitted] •Data obtained from 9 articles (14 studies) with 511 samples were meta analyzed.•Pooled levels of As and Pb in the muscle shrimps were 1.37 (95% CI: 0.66–2.08 mg/kg d.w.) and 0.58 (95% CI: 0.33–0.82 mg/kg d.w.), respectively.•The lowest and highest risk levels of oral cancer risk for both As and Pb was observed 45–54 and 15–24, respectively.•ILCR of As and Pb was higher than 10-4 and 10-3, respectively.•All groups (age) of consumers are subject to the considerable cancer risk.