Industrial research on alternative fluorocarbons

Fluorocarbons containing chlorine or bromine have been associated with stratospheric ozone depletion and the search for suitable alternatives is progressing at an accelerated pace. The Program for Alternative Fluorocarbon Toxicity Testing (PAFT), an international group representing most of the world...

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Bibliographic Details
Published inToxicology letters Vol. 68; no. 1; pp. 25 - 30
Main Author Trochimowicz, Henry J.
Format Journal Article Conference Proceeding
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.05.1993
Amsterdam Elsevier Science
Subjects
Animals
Biological and medical sciences
Chemical and industrial products toxicology. Toxic occupational diseases
Flame Retardants - toxicity
Fluorocarbon alternatives
Fluorocarbons - toxicity
HCFC-123
HCFC-124
HFC-125
HFC-134a
Hydrochlorofluorocarbons
Hydrofluorocarbons
Medical sciences
Program Development
Toxicology
Various organic compounds
HCFC-124
HCFC-123
HFC-125
Hydrofluorocarbons
Fluorocarbon alternatives
HFC-134a
Hydrochlorofluorocarbons
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Summary:Fluorocarbons containing chlorine or bromine have been associated with stratospheric ozone depletion and the search for suitable alternatives is progressing at an accelerated pace. The Program for Alternative Fluorocarbon Toxicity Testing (PAFT), an international group representing most of the world's CFC producers, has been conducting comprehensive toxicological evaluations on several possible replacements for current fire-extinguishing agents — 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123), 1-chloro-1,2,2,2-tetrafluoroethane (HCFC-124), pentafluoroethane (HFC-125), and l-fluoro-2,2,2-trifluoroethane (HFC-134a). Results from short-term experimental studies showing a low order of acute toxicity, as well as results from longer-term toxicity studies on these replacements, will be discussed.
ISSN:0378-4274
1879-3169
DOI:10.1016/0378-4274(93)90115-E