Wound healing in the trematode Schistosoma

• Published in: Tissue & cell Vol. 17; no. 1; pp. 69 - 77
• Main Authors: Popiel, Irene, Irving, Donna L., Basch, Paul F.
• Format: Journal Article
• Language: English
• Published: Sidcup Elsevier Ltd 1985; Elsevier
• Subjects: Animals; Biological and medical sciences; Cell Membrane - ultrastructure; electron microscopy; Female; Fundamental and applied biological sciences. Psychology; in vitro maintenance; Invertebrates; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Nemathelminthia. Plathelmintha; Physiology. Development; Schistosoma mansoni; Schistosoma mansoni - physiology; Schistosoma mansoni - ultrastructure; tegument repair; Wound Healing; Wounds and Injuries - pathology; in vitro maintenance; Schistosoma mansoni; electron microscopy; wound healing; tegument repair; Scanning electron microscopy; Tegument; Transmission electron microscopy; Ultrastructure; Morphology; Helmintha; Plathelmintha; Invertebrata; Wound; Cicatrization; Trematoda
• ISSN: 0040-8166; 1532-3072
• DOI: 10.1016/0040-8166(85)90016-3

The ability of adult Schistosoma mansoni to effect wound healing over an exposed surface has been demonstrated. In transected worm segments a new external plasma membrane formed over the exposed tegumental cytoplasm. An elevated leading edge of tegument developed around the margin of the wound; the surface of this region was highly convoluted and there was a proliferation of membranous bodies within its cytoplasm. Inward migration of the leading edge over the exposed internal tissues took place. The resulting new tegument lacked spines and sensory endings. There was no regeneration of basal lamina or tegumentary cytons. In vitro maintenance of worm segments for 3 weeks did not give rise to any major ultrastructural changes in the tissues away from the wound.