A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(III) pools in C. elegans

The discovery of an iron(III)-selective ratiometric fluorescent probe to detect and visualize endogenous labile iron pools in living organisms at the molecular level has been long awaited. Herein we report the first dual colorimetric and ratiometric fluorescent probe naphtho[2,1-b]-[1,10] phenanthro...

Full description

Saved in:
Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 51; no. 24; pp. 5001 - 5004
Main Authors Goel, Atul, Umar, Shahida, Nag, Pankaj, Sharma, Ashutosh, Kumar, Lalit, Shamsuzzama, Hossain, Zakir, Gayen, Jiaur R., Nazir, Aamir
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 01.01.2015
Subjects
Animals
Caenorhabditis elegans - chemistry
Chemistry
Chemistry, Multidisciplinary
Colorimetry
Ferric Compounds - analysis
Fluorescence
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Hep G2 Cells
Heterocyclic Compounds, 4 or More Rings - chemical synthesis
Heterocyclic Compounds, 4 or More Rings - chemistry
Humans
Imaging
Iron
Molecular Structure
Organisms
Physical Sciences
Pools
Quantum Theory
Science & Technology
Visualization
CELLS
CHEMOSENSOR
FE2
IRON LEVELS
FE3
BLUE
SENSORS
Online AccessGet full text

Cover

More Information
Summary:The discovery of an iron(III)-selective ratiometric fluorescent probe to detect and visualize endogenous labile iron pools in living organisms at the molecular level has been long awaited. Herein we report the first dual colorimetric and ratiometric fluorescent probe naphtho[2,1-b]-[1,10] phenanthroline NAP-3 for selective and 'direct' visualization of labile iron(III) pools in a multicellular organism, Caenorhabditis elegans.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc09798j