Zika Getting on Your Nerves? The Association with the Guillain–Barré Syndrome

Parra and colleagues 1 report in the Journal the results of a prospective study of 68 Colombian patients who had a syndrome consistent with the Guillain–Barré syndrome, 66 of whom had previously had symptoms of Zika virus (ZIKV) infection. Major strengths of this study include the documentation of a...

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Published inThe New England journal of medicine Vol. 375; no. 16; pp. 1581 - 1582
Main Authors Frontera, Jennifer A, da Silva, Ivan R.F
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 20.10.2016
Subjects
Epidemiology
Guillain-Barre Syndrome
Humans
Nerves
Viral infections
Zika Virus
Zika Virus Infection
South America
Colombia
North America
Africa
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Summary:Parra and colleagues 1 report in the Journal the results of a prospective study of 68 Colombian patients who had a syndrome consistent with the Guillain–Barré syndrome, 66 of whom had previously had symptoms of Zika virus (ZIKV) infection. Major strengths of this study include the documentation of a temporal relationship between the Guillain–Barré syndrome and ZIKV infection (marked by a substantial increase in the incidence of the Guillain–Barré syndrome after the introduction of ZIKV, from 20 to 90 cases per month throughout Colombia), the criteria applied for the diagnosis of the Guillain–Barré syndrome, and the molecular and serologic flavivirus data . . .
Bibliography:SourceType-Other Sources-1
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ObjectType-Editorial-2
ObjectType-Commentary-1
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMe1611840