Temporal lobe dysfunction and electrodermal nonresponding in schizophrenia

• Published in: Biological psychiatry (1969) Vol. 31; no. 2; pp. 159 - 170
• Main Authors: Katsanis, Joanna, Iacono, William G.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.01.1992; Elsevier Science
• Subjects: Adolescent; Adult; Adult and adolescent clinical studies; Biological and medical sciences; Brain - anatomy & histology; Brain - physiopathology; Cerebral Ventricles - anatomy & histology; Frontal Lobe - physiopathology; Galvanic Skin Response; Humans; Male; Medical sciences; Neuropsychological Tests; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Regression Analysis; Schizophrenia - diagnosis; Schizophrenia - physiopathology; Temporal Lobe - physiopathology; Tomography, X-Ray Computed; Human; Psychosis; Temporal lobe; Frontal lobe; Electrodermography; Central nervous system; Aptitude test; Electrophysiology; Schizophrenia; Psychometrics; Neuropsychologia; Brain (vertebrata)
• ISSN: 0006-3223; 1873-2402
• DOI: 10.1016/0006-3223(92)90202-B

The present study examined the biological correlates of electrodermal activity in 63 patients with DSM-III diagnosed chronic schizophrenia. Subjects were administered a battery of neuropsychological tests sensitive to temporal lobe, frontal lobe, and overall brain functioning. Brain morphology was evaluated by calculating the size of the lateral ventricles, measuring the width of the third ventricle, and rating the extent to which cortical sulci were visible. Electrodermal hyporesponsiveness was associated with impaired performance on tests that assessed temporal lobe functioning. No association was found between the brain morphology indices and electrodermal activity.