Impact of dietary anthocyanins on systemic and vascular inflammation: Systematic review and meta-analysis on randomised clinical trials

Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary anthocyanins on markers of systemic and vascular inflammation. Meta-analysis of 32 randomised controlled trials indicated that dietary anthocyanins...

Full description

Saved in:
Bibliographic Details
Published inFood and chemical toxicology Vol. 135; p. 110922
Main Authors Fallah, Aziz A., Sarmast, Elham, Fatehi, Parichehr, Jafari, Tina
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.01.2020
Subjects
adhesion
Adiponectin
Adiponectin - blood
Adiponectin - metabolism
Animals
Anthocyanins
Anthocyanins - pharmacology
bioactive compounds
Biomarkers - blood
Biomarkers - metabolism
C-reactive protein
Clinical Trials as Topic - statistics & numerical data
Cytokines - blood
Cytokines - metabolism
Humans
Inflammation
Inflammation - diet therapy
Inflammation - metabolism
Inflammatory markers
intercellular adhesion molecule-1
interleukin-1beta
interleukin-6
Meta-analysis
randomized clinical trials
systematic review
tumor necrosis factor-alpha
vascular cell adhesion molecules
Anthocyanins
Inflammation
Inflammatory markers
Adiponectin
Meta-analysis
Online AccessGet full text

Cover

Abstract Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary anthocyanins on markers of systemic and vascular inflammation. Meta-analysis of 32 randomised controlled trials indicated that dietary anthocyanins significantly decreased levels of C-reactive protein (CRP; −0.33 mg/l, 95% CI: −0.55 to −0.11, P = 0.003), interleukin-6 (IL-6; −0.41 ρg/ml, 95% CI: −0.70 to −0.13, P = 0.004), tumor necrosis factor-alpha (TNF-α; −0.64 ρg/ml, 95% CI: −1.18 to −0.09, P = 0.023), intercellular adhesion molecule-1 (−52.4 ng/ml, 95% CI: −85.7 to −19.1, P = 0.002), and vascular adhesion molecule-1 (VCAM-1; −49.6 ng/ml, 95% CI: −72.7 to −26.5, P < 0.001) while adiponectin level was significantly increased (0.75 μg/ml, 95% CI: 0.23 to 1.26, P = 0.004). The levels of interleukin-1β (IL-1β; −0.45 ρg/ml, 95% CI: −3.77 to 2.88, P = 0.793) and P-selectin (−6.98 ng/ml, 95% CI: −18.1 to 4.15, P = 0.219) did not significantly change. Subgroup analyses showed that administration of higher doses of anthocyanins (>300 mg/day) significantly decreased levels of CRP, IL-6, TNF-α, and VCAM-1. The results indicate that dietary anthocyanins reduce the levels of systemic and vascular inflammation in the subjects. •Dietary anthocyanins significantly reduced serum levels of CRP, IL-6, TNF-α, ICAM-1, and VCAM-1.•Dietary anthocyanins significantly increased serum level of adiponectin.•Anthocyanin doses of >300 mg/day are more useful to ameliorate inflammation in the subjects.
AbstractList Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary anthocyanins on markers of systemic and vascular inflammation. Meta-analysis of 32 randomised controlled trials indicated that dietary anthocyanins significantly decreased levels of C-reactive protein (CRP; −0.33 mg/l, 95% CI: −0.55 to −0.11, P = 0.003), interleukin-6 (IL-6; −0.41 ρg/ml, 95% CI: −0.70 to −0.13, P = 0.004), tumor necrosis factor-alpha (TNF-α; −0.64 ρg/ml, 95% CI: −1.18 to −0.09, P = 0.023), intercellular adhesion molecule-1 (−52.4 ng/ml, 95% CI: −85.7 to −19.1, P = 0.002), and vascular adhesion molecule-1 (VCAM-1; −49.6 ng/ml, 95% CI: −72.7 to −26.5, P < 0.001) while adiponectin level was significantly increased (0.75 μg/ml, 95% CI: 0.23 to 1.26, P = 0.004). The levels of interleukin-1β (IL-1β; −0.45 ρg/ml, 95% CI: −3.77 to 2.88, P = 0.793) and P-selectin (−6.98 ng/ml, 95% CI: −18.1 to 4.15, P = 0.219) did not significantly change. Subgroup analyses showed that administration of higher doses of anthocyanins (>300 mg/day) significantly decreased levels of CRP, IL-6, TNF-α, and VCAM-1. The results indicate that dietary anthocyanins reduce the levels of systemic and vascular inflammation in the subjects.
Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary anthocyanins on markers of systemic and vascular inflammation. Meta-analysis of 32 randomised controlled trials indicated that dietary anthocyanins significantly decreased levels of C-reactive protein (CRP; -0.33 mg/l, 95% CI: -0.55 to -0.11, P = 0.003), interleukin-6 (IL-6; -0.41 ρg/ml, 95% CI: -0.70 to -0.13, P = 0.004), tumor necrosis factor-alpha (TNF-α; -0.64 ρg/ml, 95% CI: -1.18 to -0.09, P = 0.023), intercellular adhesion molecule-1 (-52.4 ng/ml, 95% CI: -85.7 to -19.1, P = 0.002), and vascular adhesion molecule-1 (VCAM-1; -49.6 ng/ml, 95% CI: -72.7 to -26.5, P < 0.001) while adiponectin level was significantly increased (0.75 μg/ml, 95% CI: 0.23 to 1.26, P = 0.004). The levels of interleukin-1β (IL-1β; -0.45 ρg/ml, 95% CI: -3.77 to 2.88, P = 0.793) and P-selectin (-6.98 ng/ml, 95% CI: -18.1 to 4.15, P = 0.219) did not significantly change. Subgroup analyses showed that administration of higher doses of anthocyanins (>300 mg/day) significantly decreased levels of CRP, IL-6, TNF-α, and VCAM-1. The results indicate that dietary anthocyanins reduce the levels of systemic and vascular inflammation in the subjects.Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary anthocyanins on markers of systemic and vascular inflammation. Meta-analysis of 32 randomised controlled trials indicated that dietary anthocyanins significantly decreased levels of C-reactive protein (CRP; -0.33 mg/l, 95% CI: -0.55 to -0.11, P = 0.003), interleukin-6 (IL-6; -0.41 ρg/ml, 95% CI: -0.70 to -0.13, P = 0.004), tumor necrosis factor-alpha (TNF-α; -0.64 ρg/ml, 95% CI: -1.18 to -0.09, P = 0.023), intercellular adhesion molecule-1 (-52.4 ng/ml, 95% CI: -85.7 to -19.1, P = 0.002), and vascular adhesion molecule-1 (VCAM-1; -49.6 ng/ml, 95% CI: -72.7 to -26.5, P < 0.001) while adiponectin level was significantly increased (0.75 μg/ml, 95% CI: 0.23 to 1.26, P = 0.004). The levels of interleukin-1β (IL-1β; -0.45 ρg/ml, 95% CI: -3.77 to 2.88, P = 0.793) and P-selectin (-6.98 ng/ml, 95% CI: -18.1 to 4.15, P = 0.219) did not significantly change. Subgroup analyses showed that administration of higher doses of anthocyanins (>300 mg/day) significantly decreased levels of CRP, IL-6, TNF-α, and VCAM-1. The results indicate that dietary anthocyanins reduce the levels of systemic and vascular inflammation in the subjects.
Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary anthocyanins on markers of systemic and vascular inflammation. Meta-analysis of 32 randomised controlled trials indicated that dietary anthocyanins significantly decreased levels of C-reactive protein (CRP; -0.33 mg/l, 95% CI: -0.55 to -0.11, P = 0.003), interleukin-6 (IL-6; -0.41 ρg/ml, 95% CI: -0.70 to -0.13, P = 0.004), tumor necrosis factor-alpha (TNF-α; -0.64 ρg/ml, 95% CI: -1.18 to -0.09, P = 0.023), intercellular adhesion molecule-1 (-52.4 ng/ml, 95% CI: -85.7 to -19.1, P = 0.002), and vascular adhesion molecule-1 (VCAM-1; -49.6 ng/ml, 95% CI: -72.7 to -26.5, P < 0.001) while adiponectin level was significantly increased (0.75 μg/ml, 95% CI: 0.23 to 1.26, P = 0.004). The levels of interleukin-1β (IL-1β; -0.45 ρg/ml, 95% CI: -3.77 to 2.88, P = 0.793) and P-selectin (-6.98 ng/ml, 95% CI: -18.1 to 4.15, P = 0.219) did not significantly change. Subgroup analyses showed that administration of higher doses of anthocyanins (>300 mg/day) significantly decreased levels of CRP, IL-6, TNF-α, and VCAM-1. The results indicate that dietary anthocyanins reduce the levels of systemic and vascular inflammation in the subjects.
Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary anthocyanins on markers of systemic and vascular inflammation. Meta-analysis of 32 randomised controlled trials indicated that dietary anthocyanins significantly decreased levels of C-reactive protein (CRP; −0.33 mg/l, 95% CI: −0.55 to −0.11, P = 0.003), interleukin-6 (IL-6; −0.41 ρg/ml, 95% CI: −0.70 to −0.13, P = 0.004), tumor necrosis factor-alpha (TNF-α; −0.64 ρg/ml, 95% CI: −1.18 to −0.09, P = 0.023), intercellular adhesion molecule-1 (−52.4 ng/ml, 95% CI: −85.7 to −19.1, P = 0.002), and vascular adhesion molecule-1 (VCAM-1; −49.6 ng/ml, 95% CI: −72.7 to −26.5, P < 0.001) while adiponectin level was significantly increased (0.75 μg/ml, 95% CI: 0.23 to 1.26, P = 0.004). The levels of interleukin-1β (IL-1β; −0.45 ρg/ml, 95% CI: −3.77 to 2.88, P = 0.793) and P-selectin (−6.98 ng/ml, 95% CI: −18.1 to 4.15, P = 0.219) did not significantly change. Subgroup analyses showed that administration of higher doses of anthocyanins (>300 mg/day) significantly decreased levels of CRP, IL-6, TNF-α, and VCAM-1. The results indicate that dietary anthocyanins reduce the levels of systemic and vascular inflammation in the subjects. •Dietary anthocyanins significantly reduced serum levels of CRP, IL-6, TNF-α, ICAM-1, and VCAM-1.•Dietary anthocyanins significantly increased serum level of adiponectin.•Anthocyanin doses of >300 mg/day are more useful to ameliorate inflammation in the subjects.
ArticleNumber 110922
Author Jafari, Tina
Fatehi, Parichehr
Fallah, Aziz A.
Sarmast, Elham
Author_xml – sequence: 1
  givenname: Aziz A.
  surname: Fallah
  fullname: Fallah, Aziz A.
  organization: Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, 34141, Iran
– sequence: 2
  givenname: Elham
  surname: Sarmast
  fullname: Sarmast, Elham
  organization: Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, 34141, Iran
– sequence: 3
  givenname: Parichehr
  surname: Fatehi
  fullname: Fatehi, Parichehr
  organization: Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, 34141, Iran
– sequence: 4
  givenname: Tina
  orcidid: 0000-0001-7262-0135
  surname: Jafari
  fullname: Jafari, Tina
  email: tinajafari15@yahoo.com
  organization: Medical Plants Research Center, Shahrekord University of Medical Sciences, Sharhekord, Iran
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31669599$$D View this record in MEDLINE/PubMed
BookMark eNqFkU9vVCEUxYmpsdPqB3BjWLp5I_DeA56uTOOfJk1cqGtyB-6LTHgwAtNmPoFfWzrTblzU1Q3c3zmBcy7IWUwRCXnN2ZozLt9t17Ota8H4tOacTUI8IyuuVd_JfuRnZMWE0p2c-HhOLkrZMsYUV_IFOe-5lNM4TSvy53rZga00zdR5rJAPFGL9lewBoo-FpkjLoVRcvG0LR2-h2H2ATH2cAywLVJ_ie_r9yLSDpRlvPd4d4aUZdhAhHIo_WuV2mxZf0FEbfPQWAq3ZQygvyfO5DXz1MC_Jz8-fflx97W6-fbm--njT2V7L2jnQMAztr06oaUCmR9SOgRg3kxrtLOXcjwhKYi-l3LSVUKBnGDcS0VmN_SV5e_Ld5fR7j6Wa9hyLIUDEtC9GDD3XUksm_4_2nCnBBR8a-uYB3W8WdGaX_dKiNI85N0CdAJtTKRlnY309Zlcz-GA4M_eNmq1pjZr7Rs2p0abk_ygfzZ_SfDhpsCXZ2simWI_RovMZG-uSf0L9F1V-uvo
CitedBy_id crossref_primary_10_3390_foods13081227
crossref_primary_10_3233_NHA_240006
crossref_primary_10_3390_molecules29215088
crossref_primary_10_3390_antiox12091773
crossref_primary_10_1007_s00394_023_03311_9
crossref_primary_10_3390_biom13111598
crossref_primary_10_1016_j_lwt_2021_111968
crossref_primary_10_1016_j_seppur_2025_131526
crossref_primary_10_1016_j_tifs_2025_104894
crossref_primary_10_1016_j_foodhyd_2024_109797
crossref_primary_10_3390_endocrines5040035
crossref_primary_10_1016_j_foodres_2020_109379
crossref_primary_10_1016_j_neuint_2024_105900
crossref_primary_10_3390_pr12020242
crossref_primary_10_3389_fnut_2023_1255518
crossref_primary_10_1002_osp4_651
crossref_primary_10_3390_nu15194152
crossref_primary_10_1080_10408398_2021_1975638
crossref_primary_10_3390_nu13020399
crossref_primary_10_4103_pm_pm_203_20
crossref_primary_10_3390_molecules27134061
crossref_primary_10_1016_j_nutres_2023_05_009
crossref_primary_10_3390_nu15183894
crossref_primary_10_3390_foods11213377
crossref_primary_10_3389_fpls_2022_1073332
crossref_primary_10_3390_biom11060811
crossref_primary_10_1016_j_jff_2020_104069
crossref_primary_10_1021_acsabm_2c00411
crossref_primary_10_3390_molecules27134254
crossref_primary_10_1002_ptr_7961
crossref_primary_10_3390_jcm9103209
crossref_primary_10_1039_D4FO00721B
crossref_primary_10_1002_mnfr_202200112
crossref_primary_10_2478_asn_2023_0003
crossref_primary_10_1016_j_nutres_2024_02_008
crossref_primary_10_1093_nutrit_nuab086
crossref_primary_10_1080_10408398_2023_2232880
crossref_primary_10_1016_j_fbio_2023_102424
crossref_primary_10_3390_molecules26144380
crossref_primary_10_1080_19490976_2024_2446375
crossref_primary_10_1007_s10787_021_00902_y
crossref_primary_10_5937_SelSem2102011D
crossref_primary_10_1080_10408398_2021_2009761
crossref_primary_10_1016_j_foodchem_2022_134960
crossref_primary_10_1002_ptr_8124
crossref_primary_10_3390_nu13062121
crossref_primary_10_1007_s11101_023_09890_z
crossref_primary_10_3390_ph15111434
crossref_primary_10_17221_90_2023_HORTSCI
crossref_primary_10_1038_s41430_022_01175_6
crossref_primary_10_1016_j_jfca_2021_104051
crossref_primary_10_1039_D2FO01479C
crossref_primary_10_1016_j_postharvbio_2023_112580
crossref_primary_10_3390_foods11223668
crossref_primary_10_1016_j_focha_2023_100407
crossref_primary_10_1016_j_curtheres_2024_100772
crossref_primary_10_3390_nu12123781
crossref_primary_10_1002_fsn3_4451
crossref_primary_10_3390_molecules28073148
crossref_primary_10_1111_1541_4337_13070
crossref_primary_10_1080_10408398_2021_1963208
crossref_primary_10_1016_j_fct_2020_111824
crossref_primary_10_1016_j_jff_2020_103912
crossref_primary_10_1002_mnfr_202000745
crossref_primary_10_1039_D0FO01012J
crossref_primary_10_1093_nutrit_nuad121
Cites_doi 10.1136/bmj.315.7109.629
10.1016/j.lfs.2016.02.002
10.1017/S0007114510002059
10.1186/1471-2288-14-135
10.3390/nu10050569
10.1016/j.jff.2015.04.047
10.1016/j.nutres.2018.11.008
10.1016/j.clnu.2017.09.019
10.3945/jn.109.118216
10.3945/jn.114.205674
10.1159/000497226
10.3945/an.116.013052
10.1371/journal.pone.0005954
10.1017/S000711450896579X
10.1080/10408398.2015.1030064
10.3945/jn.110.125336
10.1016/j.jand.2014.11.001
10.1097/MD.0000000000000758
10.1039/C6FO01216G
10.3390/antiox7120185
10.1007/s11373-008-9261-z
10.1039/C8FO01194J
10.1089/109662003772519930
10.1042/CS20060247
10.1039/C8FO00595H
10.2307/2533446
10.1089/jmf.2016.3762
10.1016/j.jnutbio.2009.03.008
10.1089/jmf.2015.3563
10.1016/j.clnu.2014.05.008
10.1016/j.cytogfr.2011.10.001
10.4103/1735-5362.189321
10.1126/science.1230720
10.1021/jf060253x
10.1378/chest.118.2.503
10.1007/s00394-018-1643-z
10.1017/S0007114517002124
10.1681/ASN.2005050465
10.1016/j.fct.2018.07.048
10.3945/jn.110.124701
10.1016/0197-2456(86)90046-2
10.1373/clinchem.2011.167361
10.1080/21551197.2012.698219
10.1002/jnr.21205
10.1016/j.nutres.2016.12.007
10.3390/nu9101104
10.1002/mnfr.201200195
10.1002/ptr.5664
10.1136/bmj.327.7414.557
10.1016/j.nutres.2010.06.016
10.1016/j.tifs.2003.07.004
10.1016/j.jff.2013.08.015
10.1024/0300-9831/a000291
10.1016/S0014-5793(03)00509-X
10.1152/ajpendo.00699.2013
10.1159/000356053
10.1016/j.jff.2017.02.031
10.1016/j.fct.2018.02.038
10.1038/nature01320
10.1007/s00394-012-0402-9
10.1016/j.jff.2014.04.025
10.1080/03014460110048530
10.3390/nu10111639
10.1016/j.canlet.2005.04.033
10.3945/jn.109.113126
10.3945/jn.114.203190
10.1093/jn/137.8.1951
10.1016/j.nutres.2016.09.005
10.1016/j.atherosclerosis.2006.12.032
10.1186/2046-4053-4-1
10.1016/j.fct.2018.01.053
10.1016/j.jtemb.2017.09.002
10.1038/jhh.2012.4
10.3945/jn.113.188169
10.1186/s12986-016-0146-2
10.1016/j.fct.2017.01.018
10.3390/ijms19030816
10.3810/pgm.2011.01.2252
10.1016/j.fct.2018.10.029
10.1089/jmf.2011.0246
ContentType Journal Article
Copyright 2019 Elsevier Ltd
Copyright © 2019 Elsevier Ltd. All rights reserved.
Copyright_xml – notice: 2019 Elsevier Ltd
– notice: Copyright © 2019 Elsevier Ltd. All rights reserved.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7S9
L.6
DOI 10.1016/j.fct.2019.110922
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitleList AGRICOLA
MEDLINE - Academic
MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Economics
Chemistry
Public Health
EISSN 1873-6351
ExternalDocumentID 31669599
10_1016_j_fct_2019_110922
S0278691519307124
Genre Meta-Analysis
Systematic Review
Journal Article
GroupedDBID ---
--K
--M
.55
.GJ
.~1
0R~
1B1
1RT
1~.
1~5
29H
4.4
457
4G.
53G
5GY
5VS
7-5
71M
8P~
9JM
AABNK
AABVA
AACTN
AAEDT
AAEDW
AAIAV
AAIKJ
AAKOC
AALCJ
AALRI
AAOAW
AAQFI
AAQXK
AATCM
AATLK
AAXUO
ABFNM
ABFRF
ABFYP
ABGRD
ABJNI
ABLST
ABMAC
ABXDB
ABYKQ
ABZDS
ACDAQ
ACGFO
ACGFS
ACIUM
ACRLP
ADBBV
ADEZE
ADMUD
ADQTV
AEBSH
AEFWE
AEKER
AENEX
AEQOU
AFKWA
AFTJW
AFXIZ
AGHFR
AGUBO
AGYEJ
AHEUO
AHHHB
AHPSJ
AI.
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
AKIFW
ALCLG
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLECG
BLXMC
CBWCG
CS3
DU5
EBS
EFJIC
EFLBG
EJD
EO8
EO9
EP2
EP3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HLV
HMT
HVGLF
HZ~
IHE
J1W
K-O
KCYFY
KOM
LW9
M34
M41
MO0
N9A
O-L
O9-
OAUVE
OGGZJ
OZT
P-8
P-9
P2P
PC.
Q38
R2-
RIG
ROL
RPZ
SAB
SCC
SDF
SDG
SDP
SES
SEW
SPCBC
SPT
SSA
SSJ
SSP
SSZ
T5K
VH1
WUQ
X7M
ZXP
~G-
~KM
AAHBH
AATTM
AAXKI
AAYWO
AAYXX
ABWVN
ACRPL
ACVFH
ADCNI
ADNMO
AEIPS
AEUPX
AFJKZ
AFPUW
AGCQF
AGQPQ
AGRNS
AIGII
AIIUN
AKBMS
AKRWK
AKYEP
ANKPU
APXCP
BNPGV
CITATION
SSH
CGR
CUY
CVF
ECM
EFKBS
EIF
NPM
7X8
7S9
L.6
ID FETCH-LOGICAL-c386t-da8a44109d2794e085e8d0a25b975cf66f35ea76e3666b8d027a8fa5b6eedc8e3
IEDL.DBID .~1
ISSN 0278-6915
1873-6351
IngestDate Thu Jul 10 23:29:01 EDT 2025
Sun Aug 24 03:24:50 EDT 2025
Mon Jul 21 05:41:08 EDT 2025
Thu Apr 24 23:12:24 EDT 2025
Tue Jul 01 01:30:41 EDT 2025
Fri Feb 23 02:49:44 EST 2024
IsPeerReviewed true
IsScholarly true
Keywords Anthocyanins
Inflammation
Inflammatory markers
Adiponectin
Meta-analysis
Language English
License Copyright © 2019 Elsevier Ltd. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c386t-da8a44109d2794e085e8d0a25b975cf66f35ea76e3666b8d027a8fa5b6eedc8e3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ObjectType-Undefined-4
ORCID 0000-0001-7262-0135
PMID 31669599
PQID 2310721214
PQPubID 23479
ParticipantIDs proquest_miscellaneous_2431868606
proquest_miscellaneous_2310721214
pubmed_primary_31669599
crossref_citationtrail_10_1016_j_fct_2019_110922
crossref_primary_10_1016_j_fct_2019_110922
elsevier_sciencedirect_doi_10_1016_j_fct_2019_110922
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate January 2020
2020-01-00
2020-Jan
20200101
PublicationDateYYYYMMDD 2020-01-01
PublicationDate_xml – month: 01
  year: 2020
  text: January 2020
PublicationDecade 2020
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Food and chemical toxicology
PublicationTitleAlternate Food Chem Toxicol
PublicationYear 2020
Publisher Elsevier Ltd
Publisher_xml – name: Elsevier Ltd
References Savoia, Schiffrin (bib67) 2007; 112
Lee, Sorn, Park, Park (bib45) 2016; 19
Liu, Berthier-Schaad, Fallin, Fink, Tracy, Klag, Smith, Coresh (bib48) 2006; 17
Fallah, Sarmast, Habibian Dehkordi, Engardeh, Mahmoodnia, Khaledifar, Jafari (bib25) 2018; 37
Karlsen, Retterstøl, Laake, Paur, Kjølsrud-Bøhn, Sandvik, Blomhoff (bib40) 2007; 137
Johnson, Figueroa, Navaei, Wong, Kalfon, Ormsbee, Feresin, Elam, Hooshmand, Payton, Arjmandi (bib38) 2015; 115
Li, Wang, Luo, Zhao, Chen (bib46) 2017; 57
Begg, Mazumdar (bib11) 1994; 50
Basu, Du, Leyva, Sanchez, Betts, Wu, Aston, Lyons (bib7) 2010; 140
Jafari, Rostampour, Fallah, Hesami (bib35) 2017; 44
DerSimonian, Laird (bib20) 1986; 7
Demerath, Towne, Blangero, Siervogel (bib21) 2001; 28
Chew, Mathison, Kimble, McKay, Kaspar, Khoo, Chen, Blumberg (bib14) 2019; 58
Lau, Bielinski, Joseph (bib44) 2007; 85
Schwingshackl, Knüppel, Schwedhelm, Hoffmann, Missbach, Stelmach-Mardas, Dietrich, Eichelmann, Kontopanteils, Iqbal, Aleksandrova (bib69) 2016; 7
Herath, Takano-Ishikawa, Yamaki (bib30) 2003; 6
Shih, Chan, Liao, Wang, Yen (bib70) 2010; 21
Atalay, Gordillo, Roy, Rovin, Bagchi, Bagchi, Sen (bib6) 2003; 544
Jafari, Fallah, Rostampour, Mahmoodnia (bib33) 2018; 88
Rani, Deep, Singh, Palle, Yadav (bib64) 2016; 148
Basu, Betts, Nguyen, Newman, Fu, Lyons (bib9) 2014; 144
Kim, Simbo, Fang, McAlister, Roque, Banerjee, Talcott, Zhao, Kreider, Mertens-Talcott (bib42) 2018; 9
Novotny, Baer, Khoo, Gebauer, Charron (bib61) 2015; 145
Corcoran, McKay, Blumberg (bib17) 2012; 31
Marín-Echeverri, Blesso, Fernández, Galvis-Pérez, Ciro-Gómez, Núñez-Rangel, Aristizábal, Barona-Acevedo (bib55) 2018; 7
Thompson, Hosking, Pederick, Singh, Santhakumar (bib77) 2017; 118
Nathan (bib59) 2002; 420
Prokop, Anzenbacher, Mrkvicová, Pavlata, Zapletalová, Šťastník, Martinek, Kosina, Anzenbacherová (bib63) 2018; 122
Loo, Erlund, Koli, Puukka, Hellström, Wähälä, Mattila, Jula (bib50) 2016; 36
Hassellund, Flaa, Kjeldsen, Seljeflot, Karlsen, Erlund, Rostrup (bib29) 2013; 27
Dembinska-Kiec, Mykkänen, Kiec-Wilk, Mykkänen (bib19) 2008; 99
Liu, Li, Zhang, Sun, Xia (bib49) 2014; 306
Ahmet, Spangler, Shukitt-Hale, Juhaszova, Sollott, Joseph, Ingram, Talan (bib1) 2009; 4
Joo, Choi, Lee, Lee, Park, Park, Kim, Lim, Park, Jeon (bib39) 2018; 19
Xie, Vance, Kim, Lee, Caceres, Wang, Hubert, Lee, Chun, Bolling (bib82) 2017; 37
Chen, Chu, Chiou, Kuo, Chiang, Hsieh (bib13) 2006; 235
Zhu, Xia, Yang, Liu, Li, Hao, Mi, Jin, Ling (bib86) 2011; 57
Higgins, Green (bib31) 2008
Thompson, Pederick, Singh, Santhakumar (bib78) 2017; 32
Egger, Smith, Schneider, Minder (bib23) 1997; 315
Maeda-Yamamoto, Nishimura, Kitaichi, Nesumi, Monobe, Nomura, Horie, Tachibana, Nishihira (bib54) 2018; 10
Riso, Klimis-Zacas, Del Bo, Martini, Campolo, Vendrame, Møller, Loft, De Maria, Porrini (bib65) 2013; 52
Windgassen, Funtowicz, Lunsford, Harris, Mulvagh (bib81) 2011; 123
Jafari, Feizi, Askari, Fallah (bib34) 2015; 34
Wan, Wang, Liu, Tong (bib80) 2014; 14
Moher, Shamseer, Clarke, Ghersi, Liberati, Petticrew, Shekelle, Stewart (bib57) 2015; 4
Jeong, Kim, Hong, Choi, Choi, Kim, Park, Cho, Lee, Kwon, Joo (bib36) 2016; 19
Norberto, Silva, Meireles, Faria, Pintado, Calhau (bib60) 2013; 5
Basu, Fu, Wilkinson, Simmons, Wu, Betts, Du, Lyons (bib8) 2010; 30
Espinosa-Moncada, Marín-Echeverri, Galvis-Pérez, Ciro-Gómez, Aristizábal, Blesso, Fernandez, Barona-Acevedo (bib24) 2018; 10
Takikawa, Inoue, Horio, Tsuda (bib76) 2010; 140
Lopez-Castejon, Brough (bib51) 2011; 22
Stull, Cash, Johnson, Champagne, Cefalu (bib73) 2010; 140
Park, Cho, Lee, Lee, Kim, Go, Kim, Jung, Auh, Choi, Kim (bib62) 2015; 16
Asgary, Soltani, Mirvakili, Sarrafzadegan (bib4) 2016; 11
An, Kim, Lee, Kim, Kim, Kim, Kim, Choi, Kim (bib2) 2016; 30
Basu, Kurien, Tran, Maher, Schell, Masek, Barrett, Lyons, Betts, Scofield (bib10) 2018; 9
Kaume, Gbur, DiBrezzo, Howard, Devareddy (bib41) 2014; 9
Rugină, Sconţa, Leopold, Pintea, Bunea, Socaciu (bib66) 2012; 15
Gorji, Soltani, Keshvari, Ghanadian, Asgary, Sarafzadegan (bib28) 2014; 16
Soltani, Hakimi, Asgary, Ghanadian, Keshvari, Sarrafzadegan (bib71) 2014
Lu, Huang, Chang, Huang, Chi, Su, Chen, Yang (bib52) 2008; 15
Li, Zhang, Liu, Sun, Xia (bib47) 2015; 145
Maciel, do Carmo, Azevedo, Daguer, Molognoni, de Almeida, Granato, Rosso (bib53) 2018; 113
Schell, Betts, Lyons, Basu (bib68) 2019; 74
Zhang, Zhu, Song, Yao, Ya, Li, Ling, Yang (bib85) 2016; 13
Higgins, Thompson, Deeks, Altman (bib32) 2003; 327
Tabas, Glass (bib75) 2013; 339
Moazen, Amani, Homayouni Rad, Shahbazian, Ahmadi, Taha Jalali (bib56) 2013; 63
Zhang, Chen, Li, Ling, Guo (bib84) 2015; 94
Gasparrini, Giampieri, Forbes-Hernandez, Afrin, Cianciosi, Reboredo-Rodriguez, Varela-Lopez, Zhang, Quiles, Mezzetti, Bompadre (bib27) 2018; 114
Dinarello (bib22) 2000; 118
Johnson, Feresin, Navaei, Figueroa, Elam, Akhavan, Hooshmand, Pourafshar, Payton, Arjmandi (bib37) 2017; 8
Kolehmainen, Mykkänen, Kirjavainen, Leppänen, Moilanen, Adriaens, Laaksonen, Hallikainen, Puupponen‐Pimiä, Pulkkinen, Mykkänen (bib43) 2012; 56
Stintzing, Carle (bib72) 2004; 15
Vidlar, Vostalova, Ulrichova, Student, Stejskal, Reichenbach, Vrbkova, Ruzicka, Simanek (bib79) 2010; 104
Cimino, Ambra, Canali, Saija, Virgili (bib15) 2006; 54
Naruszewicz, Łaniewska, Millo, Dłużniewski (bib58) 2007; 194
Arevström, Bergh, Landberg, Wu, Rodriguez-Mateos, Waldenborg, Magnuson, Blanc, Fröbert (bib3) 2019; 62
Curtis, Kroon, Hollands, Walls, Jenkins, Kay, Cassidy (bib18) 2009; 139
Gasparrini, Forbes-Hernandez, Giampieri, Afrin, Alvarez-Suarez, Mazzoni, Mezzetti, Quiles, Battino (bib26) 2017; 102
Sun, Wu, Long, He, Gu, Yang, Liang, Wang (bib74) 2018; 120
Yang, Ling, Yang, Chen, Tian, Du, Chen, Xie, Liu, Yang (bib83) 2017; 9
Espinosa-Moncada (10.1016/j.fct.2019.110922_bib24) 2018; 10
Moher (10.1016/j.fct.2019.110922_bib57) 2015; 4
Thompson (10.1016/j.fct.2019.110922_bib77) 2017; 118
Karlsen (10.1016/j.fct.2019.110922_bib40) 2007; 137
Demerath (10.1016/j.fct.2019.110922_bib21) 2001; 28
Higgins (10.1016/j.fct.2019.110922_bib31) 2008
Dembinska-Kiec (10.1016/j.fct.2019.110922_bib19) 2008; 99
Arevström (10.1016/j.fct.2019.110922_bib3) 2019; 62
Lopez-Castejon (10.1016/j.fct.2019.110922_bib51) 2011; 22
Gasparrini (10.1016/j.fct.2019.110922_bib26) 2017; 102
Maciel (10.1016/j.fct.2019.110922_bib53) 2018; 113
Kim (10.1016/j.fct.2019.110922_bib42) 2018; 9
Kolehmainen (10.1016/j.fct.2019.110922_bib43) 2012; 56
Naruszewicz (10.1016/j.fct.2019.110922_bib58) 2007; 194
Begg (10.1016/j.fct.2019.110922_bib11) 1994; 50
Tabas (10.1016/j.fct.2019.110922_bib75) 2013; 339
Takikawa (10.1016/j.fct.2019.110922_bib76) 2010; 140
Johnson (10.1016/j.fct.2019.110922_bib38) 2015; 115
Prokop (10.1016/j.fct.2019.110922_bib63) 2018; 122
Basu (10.1016/j.fct.2019.110922_bib8) 2010; 30
Liu (10.1016/j.fct.2019.110922_bib48) 2006; 17
Li (10.1016/j.fct.2019.110922_bib46) 2017; 57
Fallah (10.1016/j.fct.2019.110922_bib25) 2018; 37
Maeda-Yamamoto (10.1016/j.fct.2019.110922_bib54) 2018; 10
Rugină (10.1016/j.fct.2019.110922_bib66) 2012; 15
Basu (10.1016/j.fct.2019.110922_bib9) 2014; 144
Stull (10.1016/j.fct.2019.110922_bib73) 2010; 140
Dinarello (10.1016/j.fct.2019.110922_bib22) 2000; 118
Ahmet (10.1016/j.fct.2019.110922_bib1) 2009; 4
Li (10.1016/j.fct.2019.110922_bib47) 2015; 145
Chew (10.1016/j.fct.2019.110922_bib14) 2019; 58
Stintzing (10.1016/j.fct.2019.110922_bib72) 2004; 15
Park (10.1016/j.fct.2019.110922_bib62) 2015; 16
Sun (10.1016/j.fct.2019.110922_bib74) 2018; 120
Curtis (10.1016/j.fct.2019.110922_bib18) 2009; 139
Zhu (10.1016/j.fct.2019.110922_bib86) 2011; 57
Jafari (10.1016/j.fct.2019.110922_bib35) 2017; 44
Liu (10.1016/j.fct.2019.110922_bib49) 2014; 306
Corcoran (10.1016/j.fct.2019.110922_bib17) 2012; 31
Kaume (10.1016/j.fct.2019.110922_bib41) 2014; 9
Lee (10.1016/j.fct.2019.110922_bib45) 2016; 19
Moazen (10.1016/j.fct.2019.110922_bib56) 2013; 63
Thompson (10.1016/j.fct.2019.110922_bib78) 2017; 32
Wan (10.1016/j.fct.2019.110922_bib80) 2014; 14
Savoia (10.1016/j.fct.2019.110922_bib67) 2007; 112
Vidlar (10.1016/j.fct.2019.110922_bib79) 2010; 104
Basu (10.1016/j.fct.2019.110922_bib7) 2010; 140
DerSimonian (10.1016/j.fct.2019.110922_bib20) 1986; 7
Nathan (10.1016/j.fct.2019.110922_bib59) 2002; 420
Marín-Echeverri (10.1016/j.fct.2019.110922_bib55) 2018; 7
Xie (10.1016/j.fct.2019.110922_bib82) 2017; 37
Gorji (10.1016/j.fct.2019.110922_bib28) 2014; 16
Zhang (10.1016/j.fct.2019.110922_bib85) 2016; 13
Gasparrini (10.1016/j.fct.2019.110922_bib27) 2018; 114
Jeong (10.1016/j.fct.2019.110922_bib36) 2016; 19
Yang (10.1016/j.fct.2019.110922_bib83) 2017; 9
Egger (10.1016/j.fct.2019.110922_bib23) 1997; 315
Cimino (10.1016/j.fct.2019.110922_bib15) 2006; 54
Lu (10.1016/j.fct.2019.110922_bib52) 2008; 15
Herath (10.1016/j.fct.2019.110922_bib30) 2003; 6
Jafari (10.1016/j.fct.2019.110922_bib34) 2015; 34
Rani (10.1016/j.fct.2019.110922_bib64) 2016; 148
Windgassen (10.1016/j.fct.2019.110922_bib81) 2011; 123
Novotny (10.1016/j.fct.2019.110922_bib61) 2015; 145
Lau (10.1016/j.fct.2019.110922_bib44) 2007; 85
Basu (10.1016/j.fct.2019.110922_bib10) 2018; 9
Norberto (10.1016/j.fct.2019.110922_bib60) 2013; 5
Zhang (10.1016/j.fct.2019.110922_bib84) 2015; 94
Hassellund (10.1016/j.fct.2019.110922_bib29) 2013; 27
Schwingshackl (10.1016/j.fct.2019.110922_bib69) 2016; 7
Higgins (10.1016/j.fct.2019.110922_bib32) 2003; 327
Atalay (10.1016/j.fct.2019.110922_bib6) 2003; 544
Loo (10.1016/j.fct.2019.110922_bib50) 2016; 36
Soltani (10.1016/j.fct.2019.110922_bib71) 2014
An (10.1016/j.fct.2019.110922_bib2) 2016; 30
Riso (10.1016/j.fct.2019.110922_bib65) 2013; 52
Chen (10.1016/j.fct.2019.110922_bib13) 2006; 235
Johnson (10.1016/j.fct.2019.110922_bib37) 2017; 8
Asgary (10.1016/j.fct.2019.110922_bib4) 2016; 11
Schell (10.1016/j.fct.2019.110922_bib68) 2019; 74
Joo (10.1016/j.fct.2019.110922_bib39) 2018; 19
Jafari (10.1016/j.fct.2019.110922_bib33) 2018; 88
Shih (10.1016/j.fct.2019.110922_bib70) 2010; 21
References_xml – volume: 144
  start-page: 830
  year: 2014
  end-page: 837
  ident: bib9
  article-title: Freeze-dried strawberries lower serum cholesterol and lipid peroxidation in adults with abdominal adiposity and elevated serum lipids
  publication-title: J. Nutr.
– volume: 315
  start-page: 629
  year: 1997
  end-page: 634
  ident: bib23
  article-title: Bias in meta-analysis detected by a simple, graphical test
  publication-title: BMJ
– volume: 9
  start-page: 202
  year: 2014
  end-page: 210
  ident: bib41
  article-title: Antioxidant-rich berries exert modest bone protective effects in postmenopausal smokers without improving biomarkers of bone metabolism
  publication-title: J. Funct. Foods
– volume: 14
  start-page: 135
  year: 2014
  ident: bib80
  article-title: Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range
  publication-title: BMC Med. Res. Methodol.
– volume: 62
  start-page: 13
  year: 2019
  end-page: 22
  ident: bib3
  article-title: Freeze-dried bilberry (
  publication-title: Nutr. Res.
– volume: 74
  start-page: 165
  year: 2019
  end-page: 174
  ident: bib68
  article-title: Raspberries improve postprandial glucose and acute and chronic inflammation in adults with type 2 diabetes
  publication-title: Ann. Nutr. Metab.
– volume: 114
  start-page: 128
  year: 2018
  end-page: 140
  ident: bib27
  article-title: Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide in human dermal fibroblast
  publication-title: Food Chem. Toxicol.
– volume: 37
  start-page: 1892
  year: 2018
  end-page: 1901
  ident: bib25
  article-title: Effect of
  publication-title: Clin. Nutr.
– volume: 122
  start-page: 225
  year: 2018
  end-page: 233
  ident: bib63
  article-title: evaluation of effect of anthocyanin-rich wheat on rat liver microsomal drug-metabolizing cytochromes P450 and on biochemical and antioxidant parameters in rats
  publication-title: Food Chem. Toxicol.
– start-page: 2014
  year: 2014
  ident: bib71
  article-title: Evaluation of the effects of
  publication-title: Evid. Based Complement Altern. Med.
– volume: 19
  start-page: 346
  year: 2016
  end-page: 352
  ident: bib36
  article-title: Black raspberry extract increased circulating endothelial progenitor cells and improved arterial stiffness in patients with metabolic syndrome: a randomized controlled trial
  publication-title: J. Med. Food
– volume: 99
  start-page: ES109
  year: 2008
  end-page: ES117
  ident: bib19
  article-title: Antioxidant phytochemicals against type 2 diabetes
  publication-title: Br. J. Nutr.
– volume: 339
  start-page: 166
  year: 2013
  end-page: 172
  ident: bib75
  article-title: Anti-inflammatory therapy in chronic disease: challenges and opportunities
  publication-title: Science
– volume: 118
  start-page: 503
  year: 2000
  end-page: 508
  ident: bib22
  article-title: Proinflammatory cytokines
  publication-title: Chest
– volume: 145
  start-page: 1185
  year: 2015
  end-page: 1193
  ident: bib61
  article-title: Cranberry juice consumption lowers markers of cardiometabolic risk, including blood pressure and circulating C-reactive protein, triglyceride, and glucose concentrations in adults
  publication-title: J. Nutr.
– volume: 22
  start-page: 189
  year: 2011
  end-page: 195
  ident: bib51
  article-title: Understanding the mechanism of IL-1β secretion
  publication-title: Cytokine Growth Factor Rev.
– volume: 10
  start-page: 1639
  year: 2018
  ident: bib24
  article-title: Evaluation of Agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome
  publication-title: Nutrients
– volume: 52
  start-page: 949
  year: 2013
  end-page: 961
  ident: bib65
  article-title: Effect of a wild blueberry (
  publication-title: Eur. J. Nutr.
– volume: 8
  start-page: 372
  year: 2017
  end-page: 380
  ident: bib37
  article-title: Effects of daily blueberry consumption on circulating biomarkers of oxidative stress, inflammation, and antioxidant defense in postmenopausal women with pre-and stage 1-hypertension: a randomized controlled trial
  publication-title: Food Funct.
– volume: 194
  start-page: e179
  year: 2007
  end-page: e184
  ident: bib58
  article-title: Combination therapy of statin with flavonoids rich extract from chokeberry fruits enhanced reduction in cardiovascular risk markers in patients after myocardial infraction (MI)
  publication-title: Atherosclerosis
– volume: 30
  start-page: 1634
  year: 2016
  end-page: 1640
  ident: bib2
  article-title: Effect of
  publication-title: Phytother Res.
– volume: 118
  start-page: 368
  year: 2017
  end-page: 374
  ident: bib77
  article-title: The effect of anthocyanin supplementation in modulating platelet function in sedentary population: a randomised, double-blind, placebo-controlled, cross-over trial
  publication-title: Br. J. Nutr.
– volume: 34
  start-page: 35
  year: 2015
  end-page: 43
  ident: bib34
  article-title: Parenteral immunonutrition in patients with acute pancreatitis: a systematic review and meta-analysis
  publication-title: Clin. Nutr.
– volume: 85
  start-page: 1010
  year: 2007
  end-page: 1017
  ident: bib44
  article-title: Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide‐activated BV2 microglia
  publication-title: J. Neurosci. Res.
– volume: 44
  start-page: 289
  year: 2017
  end-page: 297
  ident: bib35
  article-title: The association between mercury levels and autism spectrum disorders: a systematic review and meta-analysis
  publication-title: J. Trace Elem. Med. Biol.
– volume: 16
  start-page: 393
  year: 2015
  end-page: 402
  ident: bib62
  article-title: Effects of Korean black raspberry supplementation on oxidative stress and plasma antioxidant capacity in healthy male smokers
  publication-title: J. Funct. Foods
– volume: 21
  start-page: 598
  year: 2010
  end-page: 605
  ident: bib70
  article-title: Antioxidant and cognitive promotion effects of anthocyanin-rich mulberry (
  publication-title: J. Nutr. Biochem.
– volume: 36
  start-page: 1222
  year: 2016
  end-page: 1230
  ident: bib50
  article-title: Consumption of chokeberry (
  publication-title: Nutr. Res.
– volume: 32
  start-page: 131
  year: 2017
  end-page: 138
  ident: bib78
  article-title: Anthocyanin supplementation in alleviating thrombogenesis in overweight and obese population: a randomized, double-blind, placebo-controlled study
  publication-title: J. Funct. Foods
– volume: 6
  start-page: 365
  year: 2003
  end-page: 370
  ident: bib30
  article-title: Inhibitory effect of some flavonoids on tumor necrosis factor-α production in lipopolysaccharide-stimulated mouse macrophage cell line J774. 1
  publication-title: J. Med. Food
– volume: 94
  start-page: e758
  year: 2015
  ident: bib84
  article-title: A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease
  publication-title: Medicine
– volume: 140
  start-page: 1764
  year: 2010
  end-page: 1768
  ident: bib73
  article-title: Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women
  publication-title: J. Nutr.
– volume: 17
  start-page: 863
  year: 2006
  end-page: 870
  ident: bib48
  article-title: IL-6 haplotypes, inflammation, and risk for cardiovascular disease in a multiethnic dialysis cohort
  publication-title: J. Am. Soc. Nephrol.
– volume: 235
  start-page: 248
  year: 2006
  end-page: 259
  ident: bib13
  article-title: Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line
  publication-title: Cancer Lett.
– volume: 58
  start-page: 1223
  year: 2019
  end-page: 1235
  ident: bib14
  article-title: Chronic consumption of a low calorie, high polyphenol cranberry beverage attenuates inflammation and improves glucoregulation and HDL cholesterol in healthy overweight humans: a randomized controlled trial
  publication-title: Eur. J. Nutr.
– volume: 15
  start-page: 19
  year: 2004
  end-page: 38
  ident: bib72
  article-title: Functional properties of anthocyanins and betalains in plants, food, and in human nutrition
  publication-title: Trends Food Sci. Technol.
– volume: 137
  start-page: 1951
  year: 2007
  end-page: 1954
  ident: bib40
  article-title: Anthocyanins inhibit nuclear factor-κB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults
  publication-title: J. Nutr.
– volume: 7
  start-page: 994
  year: 2016
  end-page: 1004
  ident: bib69
  article-title: Perspective: NutriGrade: a scoring system to assess and judge the meta-evidence of randomized controlled trials and cohort studies in nutrition research
  publication-title: Adv. Nutr.
– volume: 102
  start-page: 1
  year: 2017
  end-page: 10
  ident: bib26
  article-title: Anti-inflammatory effect of strawberry extract against LPS-induced stress in RAW 264.7 macrophages
  publication-title: Food Chem. Toxicol.
– volume: 123
  start-page: 114
  year: 2011
  end-page: 119
  ident: bib81
  article-title: C-reactive protein and high-sensitivity C-reactive protein: an update for clinicians
  publication-title: PGM (Postgrad. Med.)
– volume: 57
  start-page: 1524
  year: 2011
  end-page: 1533
  ident: bib86
  article-title: Purified anthocyanin supplementation improves endothelial function via NO-cGMP activation in hypercholesterolemic individuals
  publication-title: Clin. Chem.
– volume: 54
  start-page: 4041
  year: 2006
  end-page: 4047
  ident: bib15
  article-title: Effect of cyanidin-3-O-glucoside on UVB-induced response in human keratinocytes
  publication-title: J. Agric. Food Chem.
– volume: 7
  start-page: 177
  year: 1986
  end-page: 188
  ident: bib20
  article-title: Meta-analysis in clinical trials
  publication-title: Contr. Clin. Trials
– volume: 7
  start-page: 185
  year: 2018
  ident: bib55
  article-title: Effect of Agraz (
  publication-title: Antioxidants
– volume: 5
  start-page: 1518
  year: 2013
  end-page: 1528
  ident: bib60
  article-title: Blueberry anthocyanins in health promotion: a metabolic overview
  publication-title: J. Funct. Foods
– volume: 145
  start-page: 742
  year: 2015
  end-page: 748
  ident: bib47
  article-title: Purified anthocyanin supplementation reduces dyslipidemia, enhances antioxidant capacity, and prevents insulin resistance in diabetic patients
  publication-title: J. Nutr.
– volume: 31
  start-page: 176
  year: 2012
  end-page: 189
  ident: bib17
  article-title: Flavonoid basics: chemistry, sources, mechanisms of action, and safety
  publication-title: J. Nutr. Gerontol. Geriatr.
– volume: 11
  start-page: 343
  year: 2016
  end-page: 348
  ident: bib4
  article-title: Evaluation of the effect of
  publication-title: Res. J. Pharm. Sci.
– volume: 544
  start-page: 252
  year: 2003
  end-page: 257
  ident: bib6
  article-title: Anti‐angiogenic property of edible berry in a model of hemangioma
  publication-title: FEBS Lett.
– volume: 420
  start-page: 846
  year: 2002
  end-page: 852
  ident: bib59
  article-title: Points of control in inflammation
  publication-title: Nature
– volume: 306
  start-page: E975
  year: 2014
  end-page: E988
  ident: bib49
  article-title: Anthocyanin increases adiponectin secretion and protects against diabetes-related endothelial dysfunction
  publication-title: Am. J. Physiol. Endocrinol. Metab.
– volume: 19
  start-page: 995
  year: 2016
  end-page: 1003
  ident: bib45
  article-title: Anthocyanin rich-black soybean testa improved visceral fat and plasma lipid profiles in overweight/obese Korean adults: a randomized controlled trial
  publication-title: J. Med. Food
– volume: 15
  start-page: 565
  year: 2008
  end-page: 576
  ident: bib52
  article-title: Adiponectin: a biomarker of obesity-induced insulin resistance in adipose tissue and beyond
  publication-title: J. Biomed. Sci.
– volume: 115
  start-page: 369
  year: 2015
  end-page: 377
  ident: bib38
  article-title: Daily blueberry consumption improves blood pressure and arterial stiffness in postmenopausal women with pre-and stage 1-hypertension: a randomized, double-blind, placebo-controlled clinical trial
  publication-title: J. Acad. Nutr. Diet.
– year: 2008
  ident: bib31
  article-title: Cochrane Handbook for Systematic Reviews of Interventions
– volume: 50
  start-page: 1088
  year: 1994
  end-page: 1101
  ident: bib11
  article-title: Operating characteristics of a rank correlation test for publication bias
  publication-title: Biometrics
– volume: 148
  start-page: 183
  year: 2016
  end-page: 193
  ident: bib64
  article-title: Oxidative stress and metabolic disorders: pathogenesis and therapeutic strategies
  publication-title: Life Sci.
– volume: 37
  start-page: 67
  year: 2017
  end-page: 77
  ident: bib82
  article-title: Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial
  publication-title: Nutr. Res.
– volume: 104
  start-page: 1181
  year: 2010
  end-page: 1189
  ident: bib79
  article-title: The effectiveness of dried cranberries (
  publication-title: Br. J. Nutr.
– volume: 4
  start-page: 1
  year: 2015
  ident: bib57
  article-title: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement
  publication-title: Syst. Rev.
– volume: 4
  year: 2009
  ident: bib1
  article-title: Blueberry-enriched diet protects rat heart from ischemic damage
  publication-title: PLoS One
– volume: 63
  start-page: 256
  year: 2013
  end-page: 264
  ident: bib56
  article-title: Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: a randomized double-blind controlled trial
  publication-title: Ann. Nutr. Metab.
– volume: 140
  start-page: 527
  year: 2010
  end-page: 533
  ident: bib76
  article-title: Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice
  publication-title: J. Nutr.
– volume: 28
  start-page: 664
  year: 2001
  end-page: 678
  ident: bib21
  article-title: The relationship of soluble ICAM-1, VCAM-1, P-selectin and E-selectin to cardiovascular disease risk factors in healthy men and women
  publication-title: Ann. Hum. Biol.
– volume: 140
  start-page: 1582
  year: 2010
  end-page: 1587
  ident: bib7
  article-title: Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome
  publication-title: J. Nutr.
– volume: 56
  start-page: 1501
  year: 2012
  end-page: 1510
  ident: bib43
  article-title: Bilberries reduce low‐grade inflammation in individuals with features of metabolic syndrome
  publication-title: Mol. Nutr. Food Res.
– volume: 112
  start-page: 375
  year: 2007
  end-page: 384
  ident: bib67
  article-title: Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions
  publication-title: Clin. Sci.
– volume: 88
  start-page: 90
  year: 2018
  end-page: 99
  ident: bib33
  article-title: Vitamin D ameliorates systolic but not diastolic blood pressure in patients with type 2 diabetes: results from a meta-analysis of randomized controlled trials
  publication-title: Int. J. Vitam. Nutr. Res.
– volume: 57
  start-page: 1729
  year: 2017
  end-page: 1741
  ident: bib46
  article-title: Health benefits of anthocyanins and molecular mechanisms: update from recent decade
  publication-title: Crit. Rev. Food Sci. Nutr.
– volume: 19
  start-page: 816
  year: 2018
  ident: bib39
  article-title: Anthocyanin-rich extract from red Chinese cabbage alleviates vascular inflammation in endothelial cells and apo E
  publication-title: Int. J. Mol. Sci.
– volume: 113
  start-page: 187
  year: 2018
  end-page: 197
  ident: bib53
  article-title: anthocyanins-rich extract: chemical stability,
  publication-title: Food Chem. Toxicol.
– volume: 10
  start-page: 569
  year: 2018
  ident: bib54
  article-title: A randomized, placebo-controlled study on the safety and efficacy of daily ingestion of green tea (
  publication-title: Nutrients
– volume: 327
  start-page: 557
  year: 2003
  end-page: 560
  ident: bib32
  article-title: Measuring inconsistency in meta-analyses
  publication-title: BMJ
– volume: 13
  start-page: 86
  year: 2016
  ident: bib85
  article-title: Effects of purified anthocyanin supplementation on platelet chemokines in hypocholesterolemic individuals: a randomized controlled trial
  publication-title: Nutr. Metab.
– volume: 139
  start-page: 2266
  year: 2009
  end-page: 2271
  ident: bib18
  article-title: Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks
  publication-title: J. Nutr.
– volume: 27
  start-page: 100
  year: 2013
  end-page: 106
  ident: bib29
  article-title: Effects of anthocyanins on cardiovascular risk factors and inflammation in pre-hypertensive men: a double-blind randomized placebo-controlled crossover study
  publication-title: J. Hum. Hypertens.
– volume: 9
  start-page: 3097
  year: 2018
  end-page: 3103
  ident: bib42
  article-title: Açaí (
  publication-title: Food Funct.
– volume: 120
  start-page: 491
  year: 2018
  end-page: 499
  ident: bib74
  article-title: Anthocyanins isolated from blueberry ameliorates CCl
  publication-title: Food Chem. Toxicol.
– volume: 9
  start-page: 1104
  year: 2017
  ident: bib83
  article-title: Role of purified anthocyanins in improving cardiometabolic risk factors in Chinese men and women with prediabetes or early untreated diabetes—a randomized controlled trial
  publication-title: Nutrients
– volume: 9
  start-page: 6218
  year: 2018
  end-page: 6226
  ident: bib10
  article-title: Strawberries decrease circulating levels of tumor necrosis factor and lipid peroxides in obese adults with knee osteoarthritis
  publication-title: Food Funct.
– volume: 30
  start-page: 462
  year: 2010
  end-page: 469
  ident: bib8
  article-title: Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome
  publication-title: Nutr. Res.
– volume: 16
  start-page: 115
  year: 2014
  end-page: 122
  ident: bib28
  article-title: The effects of cranberry on glucose levels and HbA
  publication-title: J. Shahrekord Univ. Med. Sci.
– volume: 15
  start-page: 700
  year: 2012
  end-page: 706
  ident: bib66
  article-title: Antioxidant activities of chokeberry extracts and the cytotoxic action of their anthocyanin fraction on HeLa human cervical tumor cells
  publication-title: J. Med. Food
– volume: 315
  start-page: 629
  issue: 7109
  year: 1997
  ident: 10.1016/j.fct.2019.110922_bib23
  article-title: Bias in meta-analysis detected by a simple, graphical test
  publication-title: BMJ
  doi: 10.1136/bmj.315.7109.629
– volume: 148
  start-page: 183
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib64
  article-title: Oxidative stress and metabolic disorders: pathogenesis and therapeutic strategies
  publication-title: Life Sci.
  doi: 10.1016/j.lfs.2016.02.002
– volume: 104
  start-page: 1181
  issue: 8
  year: 2010
  ident: 10.1016/j.fct.2019.110922_bib79
  article-title: The effectiveness of dried cranberries (Vaccinium macrocarpon) in men with lower urinary tract symptoms
  publication-title: Br. J. Nutr.
  doi: 10.1017/S0007114510002059
– volume: 14
  start-page: 135
  issue: 1
  year: 2014
  ident: 10.1016/j.fct.2019.110922_bib80
  article-title: Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range
  publication-title: BMC Med. Res. Methodol.
  doi: 10.1186/1471-2288-14-135
– volume: 10
  start-page: 569
  issue: 5
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib54
  article-title: A randomized, placebo-controlled study on the safety and efficacy of daily ingestion of green tea (Camellia sinensis L.) cv.“Yabukita” and “Sunrouge” on eyestrain and blood pressure in healthy adults
  publication-title: Nutrients
  doi: 10.3390/nu10050569
– volume: 16
  start-page: 393
  year: 2015
  ident: 10.1016/j.fct.2019.110922_bib62
  article-title: Effects of Korean black raspberry supplementation on oxidative stress and plasma antioxidant capacity in healthy male smokers
  publication-title: J. Funct. Foods
  doi: 10.1016/j.jff.2015.04.047
– volume: 62
  start-page: 13
  year: 2019
  ident: 10.1016/j.fct.2019.110922_bib3
  article-title: Freeze-dried bilberry (Vaccinium myrtillus) dietary supplement improves walking distance and lipids after myocardial infarction: an open-label randomized clinical trial
  publication-title: Nutr. Res.
  doi: 10.1016/j.nutres.2018.11.008
– volume: 37
  start-page: 1892
  issue: 6
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib25
  article-title: Effect of Chlorella supplementation on cardiovascular risk factors: a meta-analysis of randomized controlled trials
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2017.09.019
– volume: 140
  start-page: 527
  issue: 3
  year: 2010
  ident: 10.1016/j.fct.2019.110922_bib76
  article-title: Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice
  publication-title: J. Nutr.
  doi: 10.3945/jn.109.118216
– volume: 145
  start-page: 742
  issue: 4
  year: 2015
  ident: 10.1016/j.fct.2019.110922_bib47
  article-title: Purified anthocyanin supplementation reduces dyslipidemia, enhances antioxidant capacity, and prevents insulin resistance in diabetic patients
  publication-title: J. Nutr.
  doi: 10.3945/jn.114.205674
– volume: 74
  start-page: 165
  issue: 2
  year: 2019
  ident: 10.1016/j.fct.2019.110922_bib68
  article-title: Raspberries improve postprandial glucose and acute and chronic inflammation in adults with type 2 diabetes
  publication-title: Ann. Nutr. Metab.
  doi: 10.1159/000497226
– volume: 7
  start-page: 994
  issue: 6
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib69
  article-title: Perspective: NutriGrade: a scoring system to assess and judge the meta-evidence of randomized controlled trials and cohort studies in nutrition research
  publication-title: Adv. Nutr.
  doi: 10.3945/an.116.013052
– volume: 4
  issue: 6
  year: 2009
  ident: 10.1016/j.fct.2019.110922_bib1
  article-title: Blueberry-enriched diet protects rat heart from ischemic damage
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0005954
– volume: 99
  start-page: ES109
  issue: E-S1
  year: 2008
  ident: 10.1016/j.fct.2019.110922_bib19
  article-title: Antioxidant phytochemicals against type 2 diabetes
  publication-title: Br. J. Nutr.
  doi: 10.1017/S000711450896579X
– volume: 57
  start-page: 1729
  issue: 8
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib46
  article-title: Health benefits of anthocyanins and molecular mechanisms: update from recent decade
  publication-title: Crit. Rev. Food Sci. Nutr.
  doi: 10.1080/10408398.2015.1030064
– volume: 140
  start-page: 1764
  issue: 10
  year: 2010
  ident: 10.1016/j.fct.2019.110922_bib73
  article-title: Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women
  publication-title: J. Nutr.
  doi: 10.3945/jn.110.125336
– volume: 115
  start-page: 369
  issue: 3
  year: 2015
  ident: 10.1016/j.fct.2019.110922_bib38
  article-title: Daily blueberry consumption improves blood pressure and arterial stiffness in postmenopausal women with pre-and stage 1-hypertension: a randomized, double-blind, placebo-controlled clinical trial
  publication-title: J. Acad. Nutr. Diet.
  doi: 10.1016/j.jand.2014.11.001
– volume: 94
  start-page: e758
  issue: 20
  year: 2015
  ident: 10.1016/j.fct.2019.110922_bib84
  article-title: A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease
  publication-title: Medicine
  doi: 10.1097/MD.0000000000000758
– volume: 8
  start-page: 372
  issue: 1
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib37
  article-title: Effects of daily blueberry consumption on circulating biomarkers of oxidative stress, inflammation, and antioxidant defense in postmenopausal women with pre-and stage 1-hypertension: a randomized controlled trial
  publication-title: Food Funct.
  doi: 10.1039/C6FO01216G
– volume: 7
  start-page: 185
  issue: 12
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib55
  article-title: Effect of Agraz (Vaccinium meridionale Swartz) on high-density lipoprotein function and inflammation in women with metabolic syndrome
  publication-title: Antioxidants
  doi: 10.3390/antiox7120185
– volume: 15
  start-page: 565
  issue: 5
  year: 2008
  ident: 10.1016/j.fct.2019.110922_bib52
  article-title: Adiponectin: a biomarker of obesity-induced insulin resistance in adipose tissue and beyond
  publication-title: J. Biomed. Sci.
  doi: 10.1007/s11373-008-9261-z
– volume: 9
  start-page: 6218
  issue: 12
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib10
  article-title: Strawberries decrease circulating levels of tumor necrosis factor and lipid peroxides in obese adults with knee osteoarthritis
  publication-title: Food Funct.
  doi: 10.1039/C8FO01194J
– volume: 6
  start-page: 365
  issue: 4
  year: 2003
  ident: 10.1016/j.fct.2019.110922_bib30
  article-title: Inhibitory effect of some flavonoids on tumor necrosis factor-α production in lipopolysaccharide-stimulated mouse macrophage cell line J774. 1
  publication-title: J. Med. Food
  doi: 10.1089/109662003772519930
– volume: 112
  start-page: 375
  issue: 7
  year: 2007
  ident: 10.1016/j.fct.2019.110922_bib67
  article-title: Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions
  publication-title: Clin. Sci.
  doi: 10.1042/CS20060247
– volume: 9
  start-page: 3097
  issue: 6
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib42
  article-title: Açaí (Euterpe oleracea Mart.) beverage consumption improves biomarkers for inflammation but not glucose-or lipid-metabolism in individuals with metabolic syndrome in a randomized, double-blinded, placebo-controlled clinical trial
  publication-title: Food Funct.
  doi: 10.1039/C8FO00595H
– volume: 50
  start-page: 1088
  issue: 4
  year: 1994
  ident: 10.1016/j.fct.2019.110922_bib11
  article-title: Operating characteristics of a rank correlation test for publication bias
  publication-title: Biometrics
  doi: 10.2307/2533446
– volume: 19
  start-page: 995
  issue: 11
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib45
  article-title: Anthocyanin rich-black soybean testa improved visceral fat and plasma lipid profiles in overweight/obese Korean adults: a randomized controlled trial
  publication-title: J. Med. Food
  doi: 10.1089/jmf.2016.3762
– volume: 21
  start-page: 598
  issue: 7
  year: 2010
  ident: 10.1016/j.fct.2019.110922_bib70
  article-title: Antioxidant and cognitive promotion effects of anthocyanin-rich mulberry (Morus atropurpurea L.) on senescence-accelerated mice and prevention of Alzheimer's disease
  publication-title: J. Nutr. Biochem.
  doi: 10.1016/j.jnutbio.2009.03.008
– volume: 19
  start-page: 346
  issue: 4
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib36
  article-title: Black raspberry extract increased circulating endothelial progenitor cells and improved arterial stiffness in patients with metabolic syndrome: a randomized controlled trial
  publication-title: J. Med. Food
  doi: 10.1089/jmf.2015.3563
– volume: 34
  start-page: 35
  issue: 1
  year: 2015
  ident: 10.1016/j.fct.2019.110922_bib34
  article-title: Parenteral immunonutrition in patients with acute pancreatitis: a systematic review and meta-analysis
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2014.05.008
– volume: 22
  start-page: 189
  issue: 4
  year: 2011
  ident: 10.1016/j.fct.2019.110922_bib51
  article-title: Understanding the mechanism of IL-1β secretion
  publication-title: Cytokine Growth Factor Rev.
  doi: 10.1016/j.cytogfr.2011.10.001
– volume: 11
  start-page: 343
  issue: 4
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib4
  article-title: Evaluation of the effect of Vaccinium arctostaphylos L. fruit extract on serum inflammatory biomarkers in adult hyperlipidemic patients: a randomized double-blind placebo-controlled clinical trial
  publication-title: Res. J. Pharm. Sci.
  doi: 10.4103/1735-5362.189321
– volume: 339
  start-page: 166
  year: 2013
  ident: 10.1016/j.fct.2019.110922_bib75
  article-title: Anti-inflammatory therapy in chronic disease: challenges and opportunities
  publication-title: Science
  doi: 10.1126/science.1230720
– volume: 54
  start-page: 4041
  issue: 11
  year: 2006
  ident: 10.1016/j.fct.2019.110922_bib15
  article-title: Effect of cyanidin-3-O-glucoside on UVB-induced response in human keratinocytes
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf060253x
– volume: 118
  start-page: 503
  issue: 2
  year: 2000
  ident: 10.1016/j.fct.2019.110922_bib22
  article-title: Proinflammatory cytokines
  publication-title: Chest
  doi: 10.1378/chest.118.2.503
– volume: 58
  start-page: 1223
  issue: 3
  year: 2019
  ident: 10.1016/j.fct.2019.110922_bib14
  article-title: Chronic consumption of a low calorie, high polyphenol cranberry beverage attenuates inflammation and improves glucoregulation and HDL cholesterol in healthy overweight humans: a randomized controlled trial
  publication-title: Eur. J. Nutr.
  doi: 10.1007/s00394-018-1643-z
– year: 2008
  ident: 10.1016/j.fct.2019.110922_bib31
– volume: 118
  start-page: 368
  issue: 5
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib77
  article-title: The effect of anthocyanin supplementation in modulating platelet function in sedentary population: a randomised, double-blind, placebo-controlled, cross-over trial
  publication-title: Br. J. Nutr.
  doi: 10.1017/S0007114517002124
– volume: 17
  start-page: 863
  issue: 3
  year: 2006
  ident: 10.1016/j.fct.2019.110922_bib48
  article-title: IL-6 haplotypes, inflammation, and risk for cardiovascular disease in a multiethnic dialysis cohort
  publication-title: J. Am. Soc. Nephrol.
  doi: 10.1681/ASN.2005050465
– volume: 120
  start-page: 491
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib74
  article-title: Anthocyanins isolated from blueberry ameliorates CCl4 induced liver fibrosis by modulation of oxidative stress, inflammation and stellate cell activation in mice
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2018.07.048
– volume: 140
  start-page: 1582
  issue: 9
  year: 2010
  ident: 10.1016/j.fct.2019.110922_bib7
  article-title: Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome
  publication-title: J. Nutr.
  doi: 10.3945/jn.110.124701
– volume: 7
  start-page: 177
  issue: 3
  year: 1986
  ident: 10.1016/j.fct.2019.110922_bib20
  article-title: Meta-analysis in clinical trials
  publication-title: Contr. Clin. Trials
  doi: 10.1016/0197-2456(86)90046-2
– volume: 57
  start-page: 1524
  issue: 11
  year: 2011
  ident: 10.1016/j.fct.2019.110922_bib86
  article-title: Purified anthocyanin supplementation improves endothelial function via NO-cGMP activation in hypercholesterolemic individuals
  publication-title: Clin. Chem.
  doi: 10.1373/clinchem.2011.167361
– volume: 31
  start-page: 176
  issue: 3
  year: 2012
  ident: 10.1016/j.fct.2019.110922_bib17
  article-title: Flavonoid basics: chemistry, sources, mechanisms of action, and safety
  publication-title: J. Nutr. Gerontol. Geriatr.
  doi: 10.1080/21551197.2012.698219
– volume: 85
  start-page: 1010
  issue: 5
  year: 2007
  ident: 10.1016/j.fct.2019.110922_bib44
  article-title: Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide‐activated BV2 microglia
  publication-title: J. Neurosci. Res.
  doi: 10.1002/jnr.21205
– volume: 37
  start-page: 67
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib82
  article-title: Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial
  publication-title: Nutr. Res.
  doi: 10.1016/j.nutres.2016.12.007
– volume: 9
  start-page: 1104
  issue: 10
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib83
  article-title: Role of purified anthocyanins in improving cardiometabolic risk factors in Chinese men and women with prediabetes or early untreated diabetes—a randomized controlled trial
  publication-title: Nutrients
  doi: 10.3390/nu9101104
– volume: 56
  start-page: 1501
  issue: 10
  year: 2012
  ident: 10.1016/j.fct.2019.110922_bib43
  article-title: Bilberries reduce low‐grade inflammation in individuals with features of metabolic syndrome
  publication-title: Mol. Nutr. Food Res.
  doi: 10.1002/mnfr.201200195
– volume: 30
  start-page: 1634
  issue: 10
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib2
  article-title: Effect of Rubus occidentalis extract on metabolic parameters in subjects with prediabetes: a proof-of-concept, randomized, double‐blind, placebo‐controlled clinical trial
  publication-title: Phytother Res.
  doi: 10.1002/ptr.5664
– volume: 327
  start-page: 557
  year: 2003
  ident: 10.1016/j.fct.2019.110922_bib32
  article-title: Measuring inconsistency in meta-analyses
  publication-title: BMJ
  doi: 10.1136/bmj.327.7414.557
– volume: 30
  start-page: 462
  issue: 7
  year: 2010
  ident: 10.1016/j.fct.2019.110922_bib8
  article-title: Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome
  publication-title: Nutr. Res.
  doi: 10.1016/j.nutres.2010.06.016
– volume: 15
  start-page: 19
  issue: 1
  year: 2004
  ident: 10.1016/j.fct.2019.110922_bib72
  article-title: Functional properties of anthocyanins and betalains in plants, food, and in human nutrition
  publication-title: Trends Food Sci. Technol.
  doi: 10.1016/j.tifs.2003.07.004
– volume: 5
  start-page: 1518
  issue: 4
  year: 2013
  ident: 10.1016/j.fct.2019.110922_bib60
  article-title: Blueberry anthocyanins in health promotion: a metabolic overview
  publication-title: J. Funct. Foods
  doi: 10.1016/j.jff.2013.08.015
– volume: 88
  start-page: 90
  issue: 1–2
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib33
  article-title: Vitamin D ameliorates systolic but not diastolic blood pressure in patients with type 2 diabetes: results from a meta-analysis of randomized controlled trials
  publication-title: Int. J. Vitam. Nutr. Res.
  doi: 10.1024/0300-9831/a000291
– volume: 544
  start-page: 252
  issue: 1–3
  year: 2003
  ident: 10.1016/j.fct.2019.110922_bib6
  article-title: Anti‐angiogenic property of edible berry in a model of hemangioma
  publication-title: FEBS Lett.
  doi: 10.1016/S0014-5793(03)00509-X
– volume: 306
  start-page: E975
  issue: 8
  year: 2014
  ident: 10.1016/j.fct.2019.110922_bib49
  article-title: Anthocyanin increases adiponectin secretion and protects against diabetes-related endothelial dysfunction
  publication-title: Am. J. Physiol. Endocrinol. Metab.
  doi: 10.1152/ajpendo.00699.2013
– volume: 63
  start-page: 256
  issue: 3
  year: 2013
  ident: 10.1016/j.fct.2019.110922_bib56
  article-title: Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: a randomized double-blind controlled trial
  publication-title: Ann. Nutr. Metab.
  doi: 10.1159/000356053
– volume: 32
  start-page: 131
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib78
  article-title: Anthocyanin supplementation in alleviating thrombogenesis in overweight and obese population: a randomized, double-blind, placebo-controlled study
  publication-title: J. Funct. Foods
  doi: 10.1016/j.jff.2017.02.031
– volume: 114
  start-page: 128
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib27
  article-title: Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide in human dermal fibroblast
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2018.02.038
– volume: 420
  start-page: 846
  year: 2002
  ident: 10.1016/j.fct.2019.110922_bib59
  article-title: Points of control in inflammation
  publication-title: Nature
  doi: 10.1038/nature01320
– volume: 52
  start-page: 949
  issue: 3
  year: 2013
  ident: 10.1016/j.fct.2019.110922_bib65
  article-title: Effect of a wild blueberry (Vaccinium angustifolium) drink intervention on markers of oxidative stress, inflammation and endothelial function in humans with cardiovascular risk factors
  publication-title: Eur. J. Nutr.
  doi: 10.1007/s00394-012-0402-9
– volume: 9
  start-page: 202
  year: 2014
  ident: 10.1016/j.fct.2019.110922_bib41
  article-title: Antioxidant-rich berries exert modest bone protective effects in postmenopausal smokers without improving biomarkers of bone metabolism
  publication-title: J. Funct. Foods
  doi: 10.1016/j.jff.2014.04.025
– volume: 28
  start-page: 664
  issue: 6
  year: 2001
  ident: 10.1016/j.fct.2019.110922_bib21
  article-title: The relationship of soluble ICAM-1, VCAM-1, P-selectin and E-selectin to cardiovascular disease risk factors in healthy men and women
  publication-title: Ann. Hum. Biol.
  doi: 10.1080/03014460110048530
– volume: 10
  start-page: 1639
  issue: 11
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib24
  article-title: Evaluation of Agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome
  publication-title: Nutrients
  doi: 10.3390/nu10111639
– volume: 235
  start-page: 248
  issue: 2
  year: 2006
  ident: 10.1016/j.fct.2019.110922_bib13
  article-title: Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line
  publication-title: Cancer Lett.
  doi: 10.1016/j.canlet.2005.04.033
– volume: 139
  start-page: 2266
  issue: 12
  year: 2009
  ident: 10.1016/j.fct.2019.110922_bib18
  article-title: Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks
  publication-title: J. Nutr.
  doi: 10.3945/jn.109.113126
– volume: 145
  start-page: 1185
  issue: 6
  year: 2015
  ident: 10.1016/j.fct.2019.110922_bib61
  article-title: Cranberry juice consumption lowers markers of cardiometabolic risk, including blood pressure and circulating C-reactive protein, triglyceride, and glucose concentrations in adults
  publication-title: J. Nutr.
  doi: 10.3945/jn.114.203190
– start-page: 2014
  year: 2014
  ident: 10.1016/j.fct.2019.110922_bib71
  article-title: Evaluation of the effects of Vaccinium arctostaphylos L. Fruit extract on serum lipids and hs-CRP levels and oxidative stress in adult patients with hyperlipidemia: a randomized, double-blind, placebo-controlled clinical trial
  publication-title: Evid. Based Complement Altern. Med.
– volume: 137
  start-page: 1951
  issue: 8
  year: 2007
  ident: 10.1016/j.fct.2019.110922_bib40
  article-title: Anthocyanins inhibit nuclear factor-κB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults
  publication-title: J. Nutr.
  doi: 10.1093/jn/137.8.1951
– volume: 36
  start-page: 1222
  issue: 11
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib50
  article-title: Consumption of chokeberry (Aronia mitschurinii) products modestly lowered blood pressure and reduced low-grade inflammation in patients with mildly elevated blood pressure
  publication-title: Nutr. Res.
  doi: 10.1016/j.nutres.2016.09.005
– volume: 194
  start-page: e179
  issue: 2
  year: 2007
  ident: 10.1016/j.fct.2019.110922_bib58
  article-title: Combination therapy of statin with flavonoids rich extract from chokeberry fruits enhanced reduction in cardiovascular risk markers in patients after myocardial infraction (MI)
  publication-title: Atherosclerosis
  doi: 10.1016/j.atherosclerosis.2006.12.032
– volume: 4
  start-page: 1
  year: 2015
  ident: 10.1016/j.fct.2019.110922_bib57
  article-title: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement
  publication-title: Syst. Rev.
  doi: 10.1186/2046-4053-4-1
– volume: 113
  start-page: 187
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib53
  article-title: Hibiscus sabdariffa anthocyanins-rich extract: chemical stability, in vitro antioxidant and antiproliferative activities
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2018.01.053
– volume: 44
  start-page: 289
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib35
  article-title: The association between mercury levels and autism spectrum disorders: a systematic review and meta-analysis
  publication-title: J. Trace Elem. Med. Biol.
  doi: 10.1016/j.jtemb.2017.09.002
– volume: 27
  start-page: 100
  issue: 2
  year: 2013
  ident: 10.1016/j.fct.2019.110922_bib29
  article-title: Effects of anthocyanins on cardiovascular risk factors and inflammation in pre-hypertensive men: a double-blind randomized placebo-controlled crossover study
  publication-title: J. Hum. Hypertens.
  doi: 10.1038/jhh.2012.4
– volume: 144
  start-page: 830
  issue: 6
  year: 2014
  ident: 10.1016/j.fct.2019.110922_bib9
  article-title: Freeze-dried strawberries lower serum cholesterol and lipid peroxidation in adults with abdominal adiposity and elevated serum lipids
  publication-title: J. Nutr.
  doi: 10.3945/jn.113.188169
– volume: 13
  start-page: 86
  issue: 1
  year: 2016
  ident: 10.1016/j.fct.2019.110922_bib85
  article-title: Effects of purified anthocyanin supplementation on platelet chemokines in hypocholesterolemic individuals: a randomized controlled trial
  publication-title: Nutr. Metab.
  doi: 10.1186/s12986-016-0146-2
– volume: 102
  start-page: 1
  year: 2017
  ident: 10.1016/j.fct.2019.110922_bib26
  article-title: Anti-inflammatory effect of strawberry extract against LPS-induced stress in RAW 264.7 macrophages
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2017.01.018
– volume: 19
  start-page: 816
  issue: 3
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib39
  article-title: Anthocyanin-rich extract from red Chinese cabbage alleviates vascular inflammation in endothelial cells and apo E−/− mice
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms19030816
– volume: 123
  start-page: 114
  issue: 1
  year: 2011
  ident: 10.1016/j.fct.2019.110922_bib81
  article-title: C-reactive protein and high-sensitivity C-reactive protein: an update for clinicians
  publication-title: PGM (Postgrad. Med.)
  doi: 10.3810/pgm.2011.01.2252
– volume: 16
  start-page: 115
  issue: 5
  year: 2014
  ident: 10.1016/j.fct.2019.110922_bib28
  article-title: The effects of cranberry on glucose levels and HbA1C with type 2 diabetes patients–a randomized clinical trial
  publication-title: J. Shahrekord Univ. Med. Sci.
– volume: 122
  start-page: 225
  year: 2018
  ident: 10.1016/j.fct.2019.110922_bib63
  article-title: In vivo evaluation of effect of anthocyanin-rich wheat on rat liver microsomal drug-metabolizing cytochromes P450 and on biochemical and antioxidant parameters in rats
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2018.10.029
– volume: 15
  start-page: 700
  issue: 8
  year: 2012
  ident: 10.1016/j.fct.2019.110922_bib66
  article-title: Antioxidant activities of chokeberry extracts and the cytotoxic action of their anthocyanin fraction on HeLa human cervical tumor cells
  publication-title: J. Med. Food
  doi: 10.1089/jmf.2011.0246
SSID ssj0007176
Score 2.5321286
SecondaryResourceType review_article
Snippet Anthocyanins are natural bioactive compounds that have several health benefits. This systematic review and meta-analysis assessed the impact of dietary...
SourceID proquest
pubmed
crossref
elsevier
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 110922
SubjectTerms adhesion
Adiponectin
Adiponectin - blood
Adiponectin - metabolism
Animals
Anthocyanins
Anthocyanins - pharmacology
bioactive compounds
Biomarkers - blood
Biomarkers - metabolism
C-reactive protein
Clinical Trials as Topic - statistics & numerical data
Cytokines - blood
Cytokines - metabolism
Humans
Inflammation
Inflammation - diet therapy
Inflammation - metabolism
Inflammatory markers
intercellular adhesion molecule-1
interleukin-1beta
interleukin-6
Meta-analysis
randomized clinical trials
systematic review
tumor necrosis factor-alpha
vascular cell adhesion molecules
Title Impact of dietary anthocyanins on systemic and vascular inflammation: Systematic review and meta-analysis on randomised clinical trials
URI https://dx.doi.org/10.1016/j.fct.2019.110922
https://www.ncbi.nlm.nih.gov/pubmed/31669599
https://www.proquest.com/docview/2310721214
https://www.proquest.com/docview/2431868606
Volume 135
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEB5CemgglDZtk-0jqNBTwVlblmWpt7AkbFqaSxrITch6wJbEG-LNIZde-7c7kqwtOWQPvRl7ZIRmpJnRzHwD8DlgTlEZksLqihWsoh1uKScLKytvLDONj-XRP875_JJ9u2qutmCWa2FCWuV49qczPZ7W45vpuJrT28ViehFiZlxWwQRBPUkDJihjbZDyo9__0jzQXYnxSiQuAnWObMYcL29COmUlI-4mpU_ppqdsz6iDTl_Ci9F4JMdpfq9gy_V78HyWe7bhc64zHvZgN93IkVRo9Br-nMWCSLL0xC7cSt89EB2QA8yD7hf9QJY9SbDOOEb3luQcVYIyiGKTShy_kos19DNJZS-R-AZ_WOgR4CT8ClWgxYkMzpJcfElih5DhDVyenvyczYuxDUNhasFXhdVCo9FUSktx8zq00ZywpaZNJ9vGeM593TjdclejK9ThJ9pq4XXTcdS_Rrj6LWz3y94dAGHUa48OpWFdy6RvtSltJyptnSmloO0EyswAZUaM8tAq41rlZLRfCnmmAs9U4tkEvqyH3CaAjk3ELHNVPZIyhQpk07BPWQIUrlwIqejeLe8HFaxj9KFpxTbQoI0muEBPcQL7SXzWM60rzmUj5bv_m9h72KHB_49XQh9ge3V37z6ikbTqDuMuOIRnx2ff5-d_Ac4xEWQ
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEB7SzSGFUtL0tW3TqtBTwawty7LVW1gSdptkL0kgNyHrAVtab4g3h_yC_O2MJGuhh-whN2PPGKEZzUOa-QTww2NOUeGLwsqCZaygLS4pKzIjCqcN05UL7dHnCz67Yr-vq-sdmKZeGF9WOdj-aNODtR7eTIbZnNwsl5MLf2bGReFDEPSTlL2AXY9OVY1g92h-OltsDDJmLOHIEukzz5AON0OZl9O-orIQAXqT0qfc01PhZ3BDJ_vweogfyVEc4hvYsd0B7E3TtW34nFqN-wN4FTflSOw1egsP89ATSVaOmKVdq9t7ojx4gL5X3bLryaojEdkZeVRnSCpTJaiGqDmxy_EXudigP5PY-RKI_-EPMzVgnPhfoRc0OJDeGpL6L0m4JKR_B1cnx5fTWTbcxJDpsuHrzKhGYdyUC0Nx_VoM02xjckWrVtSVdpy7srKq5rbEbKjFT7RWjVNVy9EF68aW72HUrTr7EQijTjnMKTVrayZcrXRu2qZQxupcNLQeQ54EIPUAU-5vy_grUz3aH4kyk15mMspsDD83LDcRo2MbMUtSlf8pmkQfso3te9IAiTPnT1VUZ1d3vfQBMqbRtGBbaDBMa3iDyeIYPkT12Yy0LDgXlRCfnjewb7A3uzw_k2fzxelneEn9dkDYIfoCo_XtnT3EmGndfh3WxCMcxhQV
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Impact+of+dietary+anthocyanins+on+systemic+and+vascular+inflammation%3A+Systematic+review+and+meta-analysis+on+randomised+clinical+trials&rft.jtitle=Food+and+chemical+toxicology&rft.au=Fallah%2C+Aziz+A&rft.au=Sarmast%2C+Elham&rft.au=Fatehi%2C+Parichehr&rft.au=Jafari%2C+Tina&rft.date=2020-01-01&rft.issn=0278-6915&rft.volume=135+p.110922-&rft_id=info:doi/10.1016%2Fj.fct.2019.110922&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0278-6915&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0278-6915&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0278-6915&client=summon