Enhanced Laboratory Surveillance for the Elimination of Rubella and Congenital Rubella Syndrome in the Americas

One of the reasons the 1997 Technical Advisory Group on Vaccine-Preventable Diseases recommended acceleration of rubella and congenital rubella syndrome (CRS) prevention efforts was the fact that the enhanced measles surveillance system in the Americas found that 25% of reported measles cases were l...

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Published inThe Journal of infectious diseases Vol. 204; no. suppl_2; pp. S652 - S658
Main Authors de Filippis, Ana Maria Bispo, Icenogle, Joseph, Matus, Cuauhtémoc Ruiz, Andrus, Jon Kim
Format Journal Article
LanguageEnglish
Published United States Oxford University Press 01.09.2011
Subjects
Americas - epidemiology
Clinical Laboratory Techniques - standards
Congenital rubella syndrome
Epidemiology
Exanthema
Genotype
Humans
Infections
LABORATORY ISSUES CRITICAL FOR RUBELLA AND CRS ELIMINATION
Measles
Population Surveillance - methods
Rubella
Rubella Syndrome, Congenital - epidemiology
Rubella Syndrome, Congenital - prevention & control
Rubella virus - genetics
Rubella virus - isolation & purification
Serology
Specimens
Surveillance
Viruses
Americas
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Summary:One of the reasons the 1997 Technical Advisory Group on Vaccine-Preventable Diseases recommended acceleration of rubella and congenital rubella syndrome (CRS) prevention efforts was the fact that the enhanced measles surveillance system in the Americas found that 25% of reported measles cases were laboratory-confirmed rubella cases. Until 1997, the laboratory network primarily focused on measles diagnosis. Since 1999, due to the accelerated rubella control and CRS prevention strategy, laboratories have supported the regional measles, rubella, and CRS elimination goals. The measles-rubella laboratory network established in the Americas provides timely confirmation or rejection of suspected measles and rubella cases, and determination of the genotypic characteristics of circulating virus strains, critical information for the programs. A quality assurance process has ensured high-quality performance of procedures in the network. Challenges are occurring, but the measlesrubella laboratory network continues to adapt as the requirements of the program change, demonstrating the high quality of the laboratories in support of public health activities and elimination goals.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/jir405