Refractory ascites due to POEMS syndrome

A 52-yr-old woman developed exudative ascites 2 yr after the onset of peripheral neuropathy. Extensive evaluation revealed that the patient had no underlying liver disease, malignancy, infection, or cardiac or renal disease. The ascites initially responded to high-dose corticosteroid therapy. The pa...

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Bibliographic Details
Published inGastroenterology (New York, N.Y. 1943) Vol. 96; no. 1; p. 247
Main Authors Loeb, J M, Hauger, P H, Carney, J D, Cooper, A D
Format Journal Article
LanguageEnglish
Published United States 01.01.1989
Subjects
Ascites - etiology
Endocrine System Diseases - complications
Female
Hepatomegaly - complications
Humans
Middle Aged
Paraproteinemias - complications
Peripheral Nervous System Diseases - complications
Pigmentation Disorders - complications
Splenomegaly - complications
Syndrome
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Summary:A 52-yr-old woman developed exudative ascites 2 yr after the onset of peripheral neuropathy. Extensive evaluation revealed that the patient had no underlying liver disease, malignancy, infection, or cardiac or renal disease. The ascites initially responded to high-dose corticosteroid therapy. The patient had many clinical features of the recently described POEMS syndrome, including a persistent IgA lambda-paraprotein. Initially, her ascites responded to treatment with steroids. This is characteristic of the syndrome and should be considered in patients with POEMS syndrome and refractory ascites.
ISSN:0016-5085
1528-0012
DOI:10.1016/0016-5085(89)90789-0