Immunoglobulins in human dental caries

The penetration and complement fixation of sIgA, IgM and IgG were studied in advanced human dental caries with double-staining immunofluorescence technique. Immunoglobulins were found in dental plaque and in the superficial layers of the lesions which were exposed to saliva. sIgA was the most freque...

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Bibliographic Details
Published inArchives of oral biology Vol. 33; no. 2; pp. 135 - 141
Main Authors Pekovic, D.D., Adamkiewicz, V.W., Gornitsky, M.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 1988
Subjects
Complement C3 - immunology
Dental Caries - immunology
Dentistry
Fluorescent Antibody Technique
Humans
Immune Sera
Immunoglobulin A, Secretory - analysis
Immunoglobulin G - analysis
Immunoglobulin M - analysis
Microscopy, Fluorescence
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Summary:The penetration and complement fixation of sIgA, IgM and IgG were studied in advanced human dental caries with double-staining immunofluorescence technique. Immunoglobulins were found in dental plaque and in the superficial layers of the lesions which were exposed to saliva. sIgA was the most frequent, followed by IgG and IgM. IgG had the greatest capacity for penetration into the lesions, followed by IgM and sIgA. IgM was most frequently found in association with complement C 3.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0003-9969
1879-1506
DOI:10.1016/0003-9969(88)90057-X