Cytogenetic analysis of dedifferentiated chondrosarcoma

Cytogenetic analysis of a dedifferentiated chondrosarcoma with a fibrosarcomatous component revealed the following chromosomal complement: 47,XX,i(1)(q10),add(6)(q13),+7,+8,t(10;22) (p11.2;q11.2),+14,−15,−17,add(19)(q13.4). Chromosome studies of dedifferentiated chondrosarcoma are sparse. Three of t...

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Published inCancer genetics and cytogenetics Vol. 89; no. 1; pp. 49 - 51
Main Authors Swarts, Sarah J., Neff, James R., Johansson, Sonny L., Bridge, Julia A.
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.07.1996
Elsevier Science
Subjects
Biological and medical sciences
Chondrosarcoma - genetics
Chromosome Aberrations
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 22
Diseases of the osteoarticular system
Female
Histiocytoma, Benign Fibrous - genetics
Humans
Medical sciences
Middle Aged
Tumors of striated muscle and skeleton
X Chromosome
Human
Chromosomal aberration
Chondrosarcoma
Diseases of the osteoarticular system
Lower limb
Exploration
Fibrosarcoma
Malignant tumor
Case study
Cartilage
Tibia
Dedifferentiation
Cytogenetics
Genetics
Adult
Female
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Summary:Cytogenetic analysis of a dedifferentiated chondrosarcoma with a fibrosarcomatous component revealed the following chromosomal complement: 47,XX,i(1)(q10),add(6)(q13),+7,+8,t(10;22) (p11.2;q11.2),+14,−15,−17,add(19)(q13.4). Chromosome studies of dedifferentiated chondrosarcoma are sparse. Three of the anomalies in the present study are similar to those previously described in dedifferentiated chondrosarcoma.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0165-4608
1873-4456
DOI:10.1016/0165-4608(96)00022-2