Diabetic sclerodactyly

• Published in: Diabetes research and clinical practice Vol. 27; no. 2; pp. 153 - 157
• Main Authors: Tüzün, Binnur, Tüzün, Yalçin, Dinççaǧ, Nevin, Minareci, Özenç, Öztürk, Settar, Yilmaz, M.Temel, Satman, Ilhan, Yazici, Hasan
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 01.02.1995; Elsevier Science
• Subjects: Adult; Aged; Analysis of Variance; Associated diseases and complications; Biological and medical sciences; Biopsy; Diabetes Mellitus, Type 1 - pathology; Diabetes Mellitus, Type 1 - physiopathology; Diabetes Mellitus, Type 2 - pathology; Diabetes Mellitus, Type 2 - physiopathology; Diabetes. Impaired glucose tolerance; Diabetic Angiopathies - pathology; Diabetic Angiopathies - physiopathology; Diabetic cheiroarthropathy; Diabetic Nephropathies - physiopathology; Diabetic Neuropathies - physiopathology; Diabetic Retinopathy - physiopathology; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Female; Humans; Joints - physiopathology; Limited joint mobility; Male; Medical sciences; Middle Aged; Reference Values; Sclerodactyly; Scleroderma, Localized - pathology; Scleroderma, Localized - physiopathology; Skin - cytology; Skin - pathology; Limited joint mobility; Diabetic cheiroarthropathy; Sclerodactyly; Endocrinopathy; Human; Immunopathology; Connective tissue disease; Skin disease; Diabetes mellitus; Finger; Autoimmune disease; Review; Disease of the hand; Systemic disease; Complication; Scleroderma
• ISSN: 0168-8227; 1872-8227
• DOI: 10.1016/0168-8227(94)01023-S

Sclerodactyly is a chronic skin disorder seen together with long-term degenerative microvascular complications of diabetes mellitus. In this study, the relationship between sclerodactyly and various clinical and laboratory characteristics of diabetes mellitus have been investigated. One hundred and forty-two diabetic patients (63 type 1 and 79 type 2) and 72 healthy controls were evaluated clinically. Among the 142 diabetic patients, skin biopsies were taken from 21; 38 underwent soft tissue X-ray examination and 78 underwent periungual capillaroscopy. Among the healthy controls those with sclerodactyly were on the average 12 years older than those without ( T: 3.38; P < 0.01). On the other hand, among the patients with either type 1 or type 2 diabetes mellitus the ages were similar between those with and without sclerodactyly. There were no statistically significant differences in the prevalence of diabetic complications. The presence of complications, increased proximal nail fold capillarity, HbA 1c levels, radiological and histopathological findings were not different among those patients who had or did not have sclerodactyly.