Essential fatty acids in plasma phospholipids in schizophrenics

Blood samples were taken from schizophrenics and control patients in three different centers. The phospholipids were extracted from plasma and their fatty acid composition analyzed. Similar and consistent differences between schizophrenics and controls were observed at all three centers. The n-6 ess...

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Published inBiological psychiatry (1969) Vol. 25; no. 5; pp. 562 - 568
Main Authors Horrobin, David F., Manku, Mehar S., Morse-Fisher, Nancy, Vaddadi, Krishna S., Courtney, Paul, Glen, A.Iain M., Glen, Evelyne, Spellman, M., Bates, C.
Format Journal Article Conference Proceeding
LanguageEnglish
Published New York, NY Elsevier Inc 01.03.1989
Elsevier Science
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Summary:Blood samples were taken from schizophrenics and control patients in three different centers. The phospholipids were extracted from plasma and their fatty acid composition analyzed. Similar and consistent differences between schizophrenics and controls were observed at all three centers. The n-6 essential fatty acid levels were significantly reduced, whereas n-3 essential fatty acids were elevated.
ISSN:0006-3223
1873-2402
DOI:10.1016/0006-3223(89)90216-3