A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity

A mitochondria-targetable fluorescence probe, methyl(4-hydroxyphenyl) amino-substituted pyronin (1), was exploited, which could highly selectively sense peroxynitrite (ONOO-) within seconds.

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 51; no. 13; pp. 2721 - 2724
Main Authors Zhang, Hongxing, Liu, Jing, Sun, Yuan-Qiang, Huo, Yingying, Li, Yaohua, Liu, Weizhi, Wu, Xiao, Zhu, Nishu, Shi, Yawei, Guo, Wei
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 01.01.2015
Subjects
Animals
Cell Line
Chemistry
Chemistry, Multidisciplinary
Fluorescence
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Macrophages - chemistry
Mice
Mitochondria - metabolism
Molecular Structure
Peroxynitrous Acid - analysis
Peroxynitrous Acid - chemistry
Physical Sciences
Science & Technology
Selectivity
Substrate Specificity
Time Factors
OXIDATION
OXYGEN
NITRIC-OXIDE
SUPEROXIDE
DIACETATE
MACROPHAGES
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Summary:A mitochondria-targetable fluorescence probe, methyl(4-hydroxyphenyl) amino-substituted pyronin (1), was exploited, which could highly selectively sense peroxynitrite (ONOO-) within seconds.
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content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc09122a