Prophylactic treatment of alcoholism by lithium carbonate. A controlled study

Lithium therapy has been shown to have a therapeutic influence in reducing the drinking and incapacity by alcohol in depressive alcoholics in a prospective double-blind placebo-controlled trial conducted over one year, but it had no significant effect on non-depressed patients. Patients in the trial...

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Bibliographic Details
Published inThe Lancet (British edition) Vol. 1; no. 7984; p. 481
Main Authors Merry, J, Reynolds, C M, Bailey, J, Coppen, A
Format Journal Article
LanguageEnglish
Published England 04.09.1976
Subjects
Adult
Alcohol Drinking
Alcoholism - drug therapy
Clinical Trials as Topic
Depression - chemically induced
Depression - prevention & control
Double-Blind Method
Drug Evaluation
Female
Humans
Lithium - therapeutic use
Male
Middle Aged
Placebos
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Summary:Lithium therapy has been shown to have a therapeutic influence in reducing the drinking and incapacity by alcohol in depressive alcoholics in a prospective double-blind placebo-controlled trial conducted over one year, but it had no significant effect on non-depressed patients. Patients in the trial treated by placebo had significantly greater alcoholic morbidity if they were depressive than if they were non-depressive.
ISSN:0140-6736
DOI:10.1016/S0140-6736(76)90784-4