Muir-Torre syndrome associated with a family history of hyperlipidemia

• Published in: Journal of the American Academy of Dermatology Vol. 28; no. 2; pp. 285 - 288
• Main Authors: Ródenas, José M., Herranz, M.Teresa, Tercedor, Jesús, López, Begoña, Naranjo, Ramón, Delgado, Vicente
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.02.1993; Elsevier
• Subjects: Aged; Biological and medical sciences; Dermatology; Humans; Hyperlipidemia, Familial Combined - complications; Hyperlipidemia, Familial Combined - genetics; Intestinal Neoplasms - complications; Intestinal Neoplasms - genetics; Male; Medical sciences; Neoplastic Syndromes, Hereditary - complications; Neoplastic Syndromes, Hereditary - genetics; Pedigree; Sebaceous Gland Neoplasms - complications; Sebaceous Gland Neoplasms - genetics; Syndrome; Tumors of the skin and soft tissue. Premalignant lesions; Human; Case study; Skin disease; Concomitant disease; Family study; Male; Metabolic diseases; Lipids; Hyperlipemia; Malignant tumor; Enzymopathy; Genetic disease
• ISSN: 0190-9622; 1097-6787
• DOI: 10.1016/0190-9622(93)70035-R

The Muir-Torre syndrome is a rare disorder characterized by sebaceous neoplasms of the skin and multiple visceral malignancies. The syndrome appears to be a familial, autosomal dominant condition. We diagnosed this syndrome in a previously unreported patient and found a personal and family history of malignancies and hyperlipidemia. The association of Muir-Torre syndrome with a family history of hyperlipidemia, another autosomal dominant condition, has not been previously reported. The possible genetic relationship between the two disorders is discussed.