Effect of drugs on histamine radio-enzyme assay

The effect of over 200 drugs and other compounds on histamine radio-enzyme assay was studied. Some muscle relaxants (e.g. alcuronium), some sympathomimetics (e.g. dopamine, isoxsuprine, tyramine and possibly phenylethylamine), anti-malarial drugs, procaine, procainamide, Berenil and serotonin were p...

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Published inClinica chimica acta Vol. 180; no. 3; pp. 231 - 239
Main Authors Harvima, Rauno J., Harvima, Ilkka T., Kajander, E.Olavi, Penttilä, Ilkka M., Horsmanheimo, Maija, Fräki, Jorma E.
Format Journal Article
LanguageEnglish
Published Shannon Elsevier B.V 14.04.1989
Elsevier
Subjects
Biological and medical sciences
Drugs
Fundamental and applied biological sciences. Psychology
Histamine
Histamine - analysis
Immunoenzyme Techniques
Inflammation
Molecular and cellular biology
Pharmaceutical Preparations
Radioenzyme assay
Radioimmunoassay
Drugs
Radioenzyme assay
Histamine
Chemical mediator
Radiolabelling
Radioenzymatic assay
Quantitative analysis
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Summary:The effect of over 200 drugs and other compounds on histamine radio-enzyme assay was studied. Some muscle relaxants (e.g. alcuronium), some sympathomimetics (e.g. dopamine, isoxsuprine, tyramine and possibly phenylethylamine), anti-malarial drugs, procaine, procainamide, Berenil and serotonin were potent compounds to interfere with this assay. In some special cases still potentially inhibitory drugs seemed to be some muscle relaxants (e.g. vecuronium, pancuronium and tubocurarine), antidepressants, antihistamines (e.g. cimetidine, ranitidine and diphenhydramine), chinidin, disopyramide, tolazoline and salazosulfapyridine.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0009-8981
1873-3492
DOI:10.1016/0009-8981(89)90004-1