Synthesis and Antimicrobial Activity of Novel Polycyclic Thienopyridazine Derivatives
A series of novel thienopyridazine derivatives has been synthesized using 9-aminodibenzo[ f , h ]thieno[2,3- c ]cinnoline-8-carbonitrile as starting material. The target products exhibit promising antibacterial and antifungal properties against bacterial strains E. coli , S. aureus , B. subtilis , a...
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Published in | Chemistry of heterocyclic compounds (New York, N.Y. 1965) Vol. 55; no. 8; pp. 773 - 778 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
01.08.2019
Springer Nature Springer Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | A series of novel thienopyridazine derivatives has been synthesized using 9-aminodibenzo[
f
,
h
]thieno[2,3-
c
]cinnoline-8-carbonitrile as starting material. The target products exhibit promising antibacterial and antifungal properties against bacterial strains
E. coli
,
S. aureus
,
B. subtilis
, and
K. pneumoniae
and fungal strains
A. fumigatus
and
C. albicans
. The highest antimicrobial activity against all tested microorganisms demonstrate pyridothienocinnoline derivatives. |
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ISSN: | 0009-3122 1573-8353 |
DOI: | 10.1007/s10593-019-02534-1 |