Opioid treatment of periodic movements in sleep in patients without restless legs

Opioids may be a useful treatment for some patients with Periodic Movements of Sleep (PMS) and sleep disturbances. Four patients who had only idiopathic PMS and sleep disturbances but not Restless Legs Syndrome (RLS) were treated with various opioids. Two of the patients responded with a more than 9...

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Published inNeuropeptides (Edinburgh) Vol. 11; no. 4; pp. 181 - 184
Main Authors Kavey, Neil, Walters, Arthur S., Hening, Wayne, Gidro-Frank, Steve
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 01.05.1988
Elsevier
Subjects
Aged
Biological and medical sciences
Humans
Leg
Male
Medical sciences
Middle Aged
Miscellaneous
Movement Disorders - drug therapy
Narcotics - therapeutic use
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Sleep Wake Disorders - drug therapy
Human
Opiate receptor
Chemotherapy
Nervous system diseases
Sleep
Treatment
Sleep disorder
Opiates
Periodic motion
Mechanism of action
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Abstract Opioids may be a useful treatment for some patients with Periodic Movements of Sleep (PMS) and sleep disturbances. Four patients who had only idiopathic PMS and sleep disturbances but not Restless Legs Syndrome (RLS) were treated with various opioids. Two of the patients responded with a more than 98% decrease in the number of PMS per night of sleep and a doubling of the percentage of sleep period time spent in deep (Stages 3 and 4) sleep.
AbstractList Opioids may be a useful treatment for some patients with Periodic Movements of Sleep (PMS) and sleep disturbances. Four patients who had only idiopathic PMS and sleep disturbances but not Restless Legs Syndrome (RLS) were treated with various opioids. Two of the patients responded with a more than 98% decrease in the number of PMS per night of sleep and a doubling of the percentage of sleep period time spent in deep (Stages 3 and 4) sleep.
Author Walters, Arthur S.
Hening, Wayne
Gidro-Frank, Steve
Kavey, Neil
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  surname: Walters
  fullname: Walters, Arthur S.
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  surname: Gidro-Frank
  fullname: Gidro-Frank, Steve
  organization: Sleep Disorders Center of Columbia Presbyterian Medical Center, NYC Movement Disorder Group, USA
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Cites_doi 10.1007/BF00403581
10.1212/WNL.10.9.868
10.1176/ajp.141.8.993
10.1212/WNL.36.10.1363
10.1002/ana.410210528
10.1097/00002826-198706000-00004
10.1001/archneur.1976.00500050054010
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Issue 4
Keywords Human
Opiate receptor
Chemotherapy
Nervous system diseases
Sleep
Treatment
Sleep disorder
Opiates
Periodic motion
Mechanism of action
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  ident: 10.1016/0143-4179(88)90073-X_BIB1
  article-title: Periodic Movements in Sleep (nocturnal myloclonus) and Restless Legs Syndrome
  contributor:
    fullname: Coleman
– volume: 33
  start-page: 368
  year: 1976
  ident: 10.1016/0143-4179(88)90073-X_BIB20
  article-title: Myoclonus in familial restless legs syndrome
  publication-title: Arch Neurol
  doi: 10.1001/archneur.1976.00500050054010
  contributor:
    fullname: Boghen
– volume: 158
  start-page: 1
  year: 1945
  ident: 10.1016/0143-4179(88)90073-X_BIB3
  article-title: Restless legs. A clinical study
  publication-title: Acta Med Scand
  contributor:
    fullname: Ekbom
– volume: 9
  start-page: 72
  year: 1980
  ident: 10.1016/0143-4179(88)90073-X_BIB14
  article-title: Effects of meperidine in the Clinical Situation
  publication-title: Sleep Research
  contributor:
    fullname: Kavey
– start-page: 339
  year: 1672
  ident: 10.1016/0143-4179(88)90073-X_BIB6
  contributor:
    fullname: Willis
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Snippet Opioids may be a useful treatment for some patients with Periodic Movements of Sleep (PMS) and sleep disturbances. Four patients who had only idiopathic PMS...
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SubjectTerms Aged
Biological and medical sciences
Humans
Leg
Male
Medical sciences
Middle Aged
Miscellaneous
Movement Disorders - drug therapy
Narcotics - therapeutic use
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Sleep Wake Disorders - drug therapy
Title Opioid treatment of periodic movements in sleep in patients without restless legs
URI https://dx.doi.org/10.1016/0143-4179(88)90073-X
https://www.ncbi.nlm.nih.gov/pubmed/3419555
https://search.proquest.com/docview/78434585
Volume 11
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