Opioid treatment of periodic movements in sleep in patients without restless legs

Opioids may be a useful treatment for some patients with Periodic Movements of Sleep (PMS) and sleep disturbances. Four patients who had only idiopathic PMS and sleep disturbances but not Restless Legs Syndrome (RLS) were treated with various opioids. Two of the patients responded with a more than 9...

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Published inNeuropeptides (Edinburgh) Vol. 11; no. 4; pp. 181 - 184
Main Authors Kavey, Neil, Walters, Arthur S., Hening, Wayne, Gidro-Frank, Steve
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 01.05.1988
Elsevier
Subjects
Aged
Biological and medical sciences
Humans
Leg
Male
Medical sciences
Middle Aged
Miscellaneous
Movement Disorders - drug therapy
Narcotics - therapeutic use
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Sleep Wake Disorders - drug therapy
Human
Opiate receptor
Chemotherapy
Nervous system diseases
Sleep
Treatment
Sleep disorder
Opiates
Periodic motion
Mechanism of action
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Summary:Opioids may be a useful treatment for some patients with Periodic Movements of Sleep (PMS) and sleep disturbances. Four patients who had only idiopathic PMS and sleep disturbances but not Restless Legs Syndrome (RLS) were treated with various opioids. Two of the patients responded with a more than 98% decrease in the number of PMS per night of sleep and a doubling of the percentage of sleep period time spent in deep (Stages 3 and 4) sleep.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0143-4179
1532-2785
DOI:10.1016/0143-4179(88)90073-X