Protein C activity in renal disease

Protein C activity was determined in 19 healthy controls and in 52 patients with renal diseases, clinically divided into three groups I) Nephrotic syndrome, II) Renal insufficiency, III) Terminal uremia, requiring maintenance dialysis. In the nephrotic syndrome protein C levels were found to be norm...

Full description

Saved in:
Bibliographic Details
Published inThrombosis research Vol. 38; no. 3; pp. 243 - 249
Main Authors Sørensen, P.J., Knudsen, F., Nielsen, A.H., Dyerberg, J.
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Ltd 01.05.1985
Elsevier Science
Subjects
Adult
Aged
Biological and medical sciences
Creatinine - blood
Female
Glycoproteins - blood
Humans
Investigative techniques, diagnostic techniques (general aspects)
Kidney Failure, Chronic - blood
Male
Medical sciences
Middle Aged
Nephrotic Syndrome - blood
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Protein C
Renal Dialysis
renal disease
thrombosis
Uremia - blood
Uremia - therapy
Urinary system
renal disease
thrombosis
protein C
Renal disease
Anti C protein
Online AccessGet full text

Cover

More Information
Summary:Protein C activity was determined in 19 healthy controls and in 52 patients with renal diseases, clinically divided into three groups I) Nephrotic syndrome, II) Renal insufficiency, III) Terminal uremia, requiring maintenance dialysis. In the nephrotic syndrome protein C levels were found to be normal, but in renal insufficiency and terminal uremia the protein C activity was significantly decreased. A correlation between decreasing protein C and progressive renal failure is suggested. The reduced protein C activity may play an important role in the thrombotic tendency seen in renal diseases and uremia.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0049-3848
1879-2472
DOI:10.1016/0049-3848(85)90152-5