Antibody Response to Omicron BA.4–BA.5 Bivalent Booster

• Published in: The New England journal of medicine Vol. 388; no. 6; pp. 567 - 569
• Main Authors: Wang, Qian, Bowen, Anthony, Valdez, Riccardo, Gherasim, Carmen, Gordon, Aubree, Liu, Lihong, Ho, David D.
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 09.02.2023
• Subjects: Antibodies; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; Antibody Formation - immunology; Antibody response; Coronavirus; COVID-19 - immunology; COVID-19 - prevention & control; COVID-19 - virology; Humans; Immunization; Infections; Infectious Disease; mRNA; mRNA vaccines; Severe acute respiratory syndrome coronavirus 2; Vaccines; Vaccines, Combined - immunology; Vaccines, Combined - therapeutic use; Viral Infections

Boosting Vaccination with BA.4–BA.5 SequencesIn a small study, a bivalent mRNA vaccine targeting omicron BA.4–BA.5 sublineages resulted in similar neutralization of other SARS-CoV-2 variants as a fourth dose of a monovalent mRNA vaccine.