Immunoreactive met-enkephalin plasma concentrations in chronic alcoholics and in children born from alcoholic mothers

Several experimental and clinical observations indicate that ethanol ingestion induces specific neurochemical modifications in the Central Nervous System. In particular, an involvement of endogenous opiates has been suggested in the case of alcohol addiction. In this light, the plasma concentrations...

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Bibliographic Details
Published inLife sciences (1973) Vol. 33; no. 16; p. 1581
Main Authors Govoni, S, Bosio, A, Di Monda, E, Fazzari, G, Spano, P F, Trabucchi, M
Format Journal Article
LanguageEnglish
Published Netherlands 17.10.1983
Subjects
Adult
Alcoholism - blood
Child
Child, Preschool
Enkephalin, Methionine - blood
Female
Humans
Male
Pregnancy
Prenatal Exposure Delayed Effects
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Summary:Several experimental and clinical observations indicate that ethanol ingestion induces specific neurochemical modifications in the Central Nervous System. In particular, an involvement of endogenous opiates has been suggested in the case of alcohol addiction. In this light, the plasma concentrations of met-enkephalin immunoreactive peptides (ME-IR) have been measured in selected groups of chronic alcoholics and in children whose mothers were ethanol addicts. Both groups revealed a marked reduction of ME-IR plasma concentrations when compared with sex and age matched controls.
ISSN:0024-3205
DOI:10.1016/0024-3205(83)90699-9