Urinary mutagen levels in smokers

Urinary mutagen levels were measured over an 8-week period in a group of 13 smokers. Individual urinary mutagen levels were observed to be relatively constant and while there was a general correlation between mutagen excretion levels and cigarette consumption, individuals' excretion levels coul...

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Bibliographic Details
Published inCancer letters Vol. 20; no. 1; pp. 37 - 42
Main Authors Jaffe, Robert L., Nicholson, William J., Garro, Anthony J.
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.08.1983
Elsevier
Subjects
Biological and medical sciences
Chemical mutagenesis
Dose-Response Relationship, Drug
Humans
Medical sciences
Mutagenicity Tests
Mutagens - pharmacology
Mutagens - urine
Salmonella typhimurium - genetics
Smoking
Tars - pharmacology
Toxicology
Urine
Bacteria
Mutagenicity testing
Salmonella typhimurium
Tobacco smoking
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Summary:Urinary mutagen levels were measured over an 8-week period in a group of 13 smokers. Individual urinary mutagen levels were observed to be relatively constant and while there was a general correlation between mutagen excretion levels and cigarette consumption, individuals' excretion levels could not be predicted on the basis of either the numbers of cigarettes smoked or the tar content of the cigarettes.
ISSN:0304-3835
1872-7980
DOI:10.1016/0304-3835(83)90184-2