Repeated plasma volume determination with the Evans Blue dye dilution technique: The method and a computer program

This paper describes a reliable multiple sample Evans Blue dye dilution technique and a Pascal program which computes plasma and blood volume on the basis of this technique. The program performs needed corrections and dye disappearance curve fitting. It provides menudriven facilities for data correc...

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Bibliographic Details
Published inComputers in biology and medicine Vol. 21; no. 1; pp. 35 - 41
Main Authors Foldager, N., Blomqvist, C.G.
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 1991
New York, NY Elsevier Science
Subjects
Azo compounds
Biological and medical sciences
Blood Volume
Computers
Diagnosis, Computer-Assisted
Evans Blue
Indicator dilution technique
Investigative techniques of hemodynamics
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Pascal
Plasma volume
Reproducibility of Results
Software
Space life sciences
User-Computer Interface
Computers
Blood volume
Plasma volume
Azo compounds
Software
Pascal
Indicator dilution technique
Staining
Computer program
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Summary:This paper describes a reliable multiple sample Evans Blue dye dilution technique and a Pascal program which computes plasma and blood volume on the basis of this technique. The program performs needed corrections and dye disappearance curve fitting. It provides menudriven facilities for data correction, graphic display of the dye disappearance curve, and print-out of all the involved data. Means±S.E.M. for three plasma volume determinations in each of six resting subjects were: 3239±96 ml, 3189±81 ml, and 3187±102 ml. The differences were not statistically significant.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0010-4825
1879-0534
DOI:10.1016/0010-4825(91)90033-6