Chemical-constituent diversity of Tridax procumbens
Three new phytochemicals, a polyacetylene, 1,2-dihydrodendroarboreol B ( 1 ), an ionone derivative, (3S,5R,6S,7E)-3-tetradecanoate-5,6-epoxy-β-ionone ( 4 ), and a flavonol diglycoside, quercetagetin-3,6,4′-trimethoxy-7-O-neohesperidoside ( 38 ), along with 35 known compounds with diverse structures,...
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Published in | Canadian journal of chemistry Vol. 86; no. 9; pp. 892 - 898 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Ottawa, Canada
NRC Research Press
01.09.2008
Canadian Science Publishing Canadian Science Publishing NRC Research Press |
Subjects | |
Online Access | Get full text |
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Summary: | Three new phytochemicals, a polyacetylene, 1,2-dihydrodendroarboreol B (
1
), an ionone derivative, (3S,5R,6S,7E)-3-tetradecanoate-5,6-epoxy-β-ionone (
4
), and a flavonol diglycoside, quercetagetin-3,6,4′-trimethoxy-7-O-neohesperidoside (
38
), along with 35 known compounds with diverse structures, were isolated from the EtOH extract of the aerial parts of Tridax procumbens. The structures of
1
,
4
, and
38
were determined on the basis of comprehensive methods including UV, IR, NMR, HR-ESI-MS, and CD, and by comparison of the spectroscopic data with those reported for structurally related compounds. Compounds
4
, (3S,5R,6S,7E)-5,6-epoxy-3-hydroxy-7-megastigmene-9-one (
5
), and icariside B
1
(
12
) were tested for their abilities to inhibit SGC-7901 and HL-60 cells. The antioxidant activities of quercetagetin-3,6,4′-trimethoxyl-7-O-β-
D
-glucopyranoside (
36
), quercetin-3-methoxyl-4′-O-β-
D
-glucoside (
37
), and
38
were evaluated by measuring their free-radical-scavenging effects, using the DPPH free-radical method.Key words: Tridax procumbens, polyacetylene, ionone, flavonol, cytotoxicity, antioxidant activities. |
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ISSN: | 0008-4042 1480-3291 |
DOI: | 10.1139/v08-097 |