Ruthenium-catalyzed double-fold C-H tertiary alkoxycarbonylation of arenes using di-tert-butyl dicarbonate

• Published in: Chemical communications (Cambridge, England) Vol. 50; no. 91; pp. 14129 - 14132
• Main Authors: Hong, Xiaohu, Wang, Hao, Liu, Bingxin, Xu, Bin
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 01.01.2014
• Subjects: Aromatic compounds; Benzene Derivatives - chemical synthesis; Benzene Derivatives - chemistry; Carbonates - chemistry; Catalysis; Chemistry; Chemistry, Multidisciplinary; Esterification; Molecular Structure; Organometallic Compounds - chemistry; Physical Sciences; Reagents; Ruthenium - chemistry; Science & Technology; DIRECTING GROUP; FUNCTIONALIZATION; ORGANIC-SYNTHESIS; ACTIVATION; CONVENIENT METHOD; ESTERS; CALCIUM HALIDES; BONDS EFFICIENT ACCESS; CARBON-HYDROGEN BONDS; CLEAVAGE

An efficient ruthenium-catalyzed double-fold C-H alkoxycarbonylation of arenes was developed using di-tert-butyl dicarbonate as the tertiary esterification reagent, which leads to a direct route to valuable 2,6-dicarboxylated products.